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Invitrogen
WNT3 Polyclonal Antibody
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Product Details
PA5-18516
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (CGRGHNTRTEKRKEK) corresponding to the internal amino acids of WNT3 (aa 315-330).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10979520
Product Specific Information
This antibody is predicted to react with canine and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
Target Information
WNT3, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MGC131950; MGC138321; MGC138323; Proto-oncogene Int-4 homolog; Proto-oncogene Wnt-3; wingless-type MMTV integration site family member 3; wingless-type MMTV integration site family, member 3; WNT-3 proto-oncogene protein
Gene Aliases: INT4; TETAMS; WNT3
UniProt ID: (Human) P56703
Entrez Gene ID: (Human) 7473
cell morphogenesis
mesoderm formation
gamete generation
axon guidance
anterior/posterior axis specification
dorsal/ventral axis specification
positive regulation of gene expression
Wnt signaling pathway
positive regulation of Wnt signaling pathway
neuron differentiation
embryonic forelimb morphogenesis
embryonic hindlimb morphogenesis
canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
canonical Wnt signaling pathway involved in osteoblast differentiation
cell fate commitment
positive regulation of collateral sprouting in absence of injury
negative regulation of axon extension involved in axon guidance
Spemann organizer formation at the anterior end of the primitive streak
canonical Wnt signaling pathway
limb bud formation
head morphogenesis
mammary gland epithelium development
cellular response to retinoic acid
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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