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Invitrogen
WNT6 Polyclonal Antibody
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Product Details
PA5-34326
Product Specifications
Species Reactivity
Human,
Mouse,
Rabbit,
Rat,
Bovine,
Dog,
Horse,
Hamster
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 20 amino acid peptide from N-terminus of human WNT6.
Conjugate
Form
Liquid
Concentration
0.69 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2551678
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse, Rabbit (100%).
Target Information
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Wnt-6; wingless-related MMTV integration site 6; wingless-type MMTV integration site family member 6; wingless-type MMTV integration site family, member 6
Gene Aliases: AA409270; BOS_2126; I79_015321; Wnt-6; WNT6
UniProt ID: (Human) Q9Y6F9, (Mouse) P22727
Entrez Gene ID: (Rabbit) 100348986, (Bovine) 505075, (Human) 7475, (Dog) 488527, (Rat) 316526, (Chinese hamster) 100751289, (Mouse) 22420
branching involved in ureteric bud morphogenesis
biological_process
axis specification
positive regulation of gene expression
Wnt signaling pathway
neuron differentiation
odontogenesis of dentin-containing tooth
cell fate commitment
positive regulation of transcription, DNA-templated
epithelial-mesenchymal cell signaling
positive regulation of tooth mineralization
nephron tubule formation
nephron tubule development
cornea development in camera-type eye
cellular response to retinoic acid
signal transduction
cell-cell signaling
multicellular organism development
organ morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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