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Abnova
WNT8A Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
WNT8A Antibody (H00007478-B01P) in WB
Western Blot analysis of WNT8A expression in transfected 293T cell line (H00007478-T01) by WNT8A MaxPab polyclonal antibody.
Lane 1: WNT8A transfected lysate(38.61 KDa).
Lane 2: Non-transfected lysate.
Lane 1: WNT8A transfected lysate(38.61 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00007478-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
WNT8A (NP_490645, 1 a.a. approximately 351 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MGNLFMLWAA LGICCAAFSA SAWSVNNFLI TGPKAYLTYT TSVALGAQSG IEECKFQFAW ERWNCPENAL QLSTHNRLRS ATRETSFIHA ISSAGVMYII TKNCSMGDFE NCGCDGSNNG KTGGHGWIWG GCSDNVEFGE RISKLFVDSL EKGKDARALM NLHNNRAGRL AVRATMKRTC KCHGISGSCS IQTCWLQLAE FREMGDYLKA KYDQALKIEM DKRQLRAGNS AEGHWVPAEA FLPSAEAELI FLEESPDYCT CNSSLGIYGT EGRECLQNSH NTSRWERRSC GRLCTECGLQ VEERKTEVIS SCNCKFQWCC TVKCDQCRHV VSKYYCARSP GSAQSLGKGS A
Target Information
WNT8A, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Wnt-8a; Protein Wnt-8d; wingless-type MMTV integration site family member 8A; wingless-type MMTV integration site family, member 8A; WNT8d
Gene Aliases: WNT8A; WNT8D
UniProt ID: (Human) Q9H1J5
Entrez Gene ID: (Human) 7478
neural crest cell fate commitment
Wnt signaling pathway
neuron differentiation
response to retinoic acid
regulation of transcription involved in anterior/posterior axis specification
canonical Wnt signaling pathway involved in neural crest cell differentiation
palate development
canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
beta-catenin destruction complex disassembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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