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Invitrogen
WNT8A Polyclonal Antibody
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Product Details
PA5-33116
Product Specifications
Species Reactivity
Bat,
Horse,
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 14 amino acid peptide from internal region of human WNT8A.
Conjugate
Form
Liquid
Concentration
0.7 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550575
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Bat, Elephant, Panda, Horse (100%); Bovine, Dog (93%); Rabbit (86%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
WNT8A, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Wnt-8a; Protein Wnt-8d; wingless-type MMTV integration site family member 8A; wingless-type MMTV integration site family, member 8A; WNT8d
Gene Aliases: WNT8A; WNT8D
UniProt ID: (Human) Q9H1J5
Entrez Gene ID: (Human) 7478
neural crest cell fate commitment
Wnt signaling pathway
neuron differentiation
response to retinoic acid
regulation of transcription involved in anterior/posterior axis specification
canonical Wnt signaling pathway involved in neural crest cell differentiation
palate development
canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
beta-catenin destruction complex disassembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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