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WWC2 Antibody (PA5-116880) in IHC (P)
Immunohistochemistry analysis of WWC2 in paraffin-embedded mouse kidney. Samples were incubated with WWC2 Polyclonal antibody (Product # PA5-116880) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-116880
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 160-430 of human WWC2 (NP_0792255)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2901510
Product Specific Information
Positive Samples: U20S, Mouse lung
Immunogen sequence: DPDILKAEIS TTRLRVKKLK RELSQMKQEL LYKEQGFETL QQIDKKMSGG QSGYELSEAK AILTELKSIR KAISSGEKEK QDLMQSLAKL QERFHLDQNI GRSEPDLRCS PVNSHLCLSR QTLDAGSQTS ISGDIGVRSR SNLAEKVRLS LQYEEAKRSM ANLKIELSKL DSEAWPGALD IEKEKLMLIN EKEELLKELQ FVTPQKRTQD ELERLEAERQ RLEEELLSVR GTPSRALAER LRLEERRKEL LQKLEETTKL TTYLHSQLKS L
Target Information
This gene encodes a member of the WW-and-C2-domain-containing family of proteins. Members of this family have two N-terminal WW domains that mediate binding to target proteins harboring L/PPxY motifs, an internal C2 domain for membrane association, and C-terminal alpha protein kinase C binding sites and class III PDZ domain-interaction motifs. Proteins of this family are able to form homo- and heterodimers and to modulate hippo pathway signaling.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BH-3-only member B; BH3-only member B protein; Protein WWC2; WW domain-containing protein 2; WW, C2 and coiled-coil domain containing 2
Gene Aliases: 5330431C14Rik; AU022508; BOMB; C85457; D8Ertd594e; MNCb-4173; RGD1559427; WWC2
UniProt ID: (Human) Q6AWC2, (Mouse) Q6NXJ0
Entrez Gene ID: (Human) 80014, (Rat) 498630, (Mouse) 52357
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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