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Proteintech
WWP2 Polyclonal Antibody
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Product Details
12197-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
WWP2 Fusion Protein Ag2835 (1-355 aa encoded by BC013645)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MASASSSRA GVALPFEKSQ LTLKVVSAKP KVHNRQPRIN SYVEVAVDGL PSETKKTGKR IGSSELLWNE IIILNVTAQS HLDLKVWSCH TLRNELLGTA SVNLSNVLKN NGGKMENMQL TLNLQTENKG SVVSGGELTI FLDGPTVDLG NVPNGSALTD GSQLPSRDSS GTAVAPENRH QPPSTNCFGG RSRTHRHSGA SARTTPATGE QSPGARSRHR QPVKNSGHSG LANGTVNDEP TTATDPEEPS VVGVTSPPAA PLSVTPNPNT TSLPAPATPA EGEEPSTSGT QQLPAAAQAP DALPAGWEQR ELPNGRVYYV DHNTKTTTWE RPLPPGWEKR TDPRGRFYYV DHNTRT (1-355 aa encoded by B C013645)
Target Information
This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. The encoded protein contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AIP2; atrophin-1 interacting protein 2; Atrophin-1-interacting protein 2; HECT-type E3 ubiquitin transferase WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2; WW domain-containing protein 2; WW domain-containing protein 4
Gene Aliases: 1300010O06Rik; AA690238; AIP2; AW554328; WWP2; WWp2-like
UniProt ID: (Human) O00308, (Mouse) Q9DBH0
Entrez Gene ID: (Human) 11060, (Rat) 291999, (Mouse) 66894
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription factor binding
ubiquitin-protein transferase activity
protein binding
transcription factor binding
ligase activity
ubiquitin protein ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
negative regulation of gene expression
protein ubiquitination
negative regulation of transporter activity
regulation of ion transmembrane transport
regulation of membrane potential
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of protein transport
protein autoubiquitination
protein K63-linked ubiquitination
regulation of potassium ion transmembrane transporter activity
cellular protein modification process
viral entry into host cell
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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