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Proteintech
Willin Polyclonal Antibody
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Product Details
21039-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Willin Fusion Protein Ag15375 (359-622 aa encoded by BC029870)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Although willin is found in the cytoplasm and membrane, it localizes to the nuclei of almost all tumors. This antibody was raised against the C-terminal region of human FRMD6 protein and is expected to recognize the endogenous FRMD6.
Immunogen sequence: LDMDQLEKR SRASGSSAGS MKHKRLSRHS TASHSSSHTS GIEADTKPRD TGPEDSYSSS AIHRKLKTCS SMTSHGSSHT SGVESGGKDR LEEDLQDDEI EMLVDDPRDL EQMNEESLEV SPDMCIYITE DMLMSRKLNG HSGLIVKEIG SSTSSSSETV VKLRGQSTDS LPQTICRKPK TSTDRHSLSL DDIRLYQKDF LRIAGLCQDT AQSYTFGCGH ELDEEGLYCN SCLAQQCINI QDAFPVKRTS KYFSLDLTHD EVPEFVV (359-622 aa encoded by BC029870 )
Target Information
The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 4.1 ezrin radixin moesin (FERM)-containing protein; expanded homolog; FERM domain-containing protein 163SCII; FERM domain-containing protein 6; FERM-domain-containing protein 163SCII; MGC17921; Willin
Gene Aliases: 2610019M19Rik; 4930488L10Rik; AW212977; c14_5320; C14orf31; EX1; FRMD6; Willin
UniProt ID: (Human) Q96NE9, (Mouse) Q8C0V9
Entrez Gene ID: (Human) 122786, (Rat) 257646, (Mouse) 319710
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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