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Bioss
Wnt16 Polyclonal Antibody
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Product Details
BS-9476R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Wnt16, amino acids 220-265.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen. WNT15 is also a ligand for members of the frizzled family of seven transmembrane receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Wnt-16; wingless-related MMTV integration site 16; wingless-type MMTV integration site family member 16; wingless-type MMTV integration site family member 16b; wingless-type MMTV integration site family, member 16
Gene Aliases: E130309I19Rik; WNT16
UniProt ID: (Human) Q9UBV4, (Mouse) Q9QYS1
Entrez Gene ID: (Human) 51384, (Rat) 500047, (Mouse) 93735
optic cup formation involved in camera-type eye development
positive regulation of gene expression
positive regulation of phosphatidylinositol 3-kinase signaling
Wnt signaling pathway
neuron differentiation
keratinocyte differentiation
keratinocyte proliferation
cell fate commitment
positive regulation of JNK cascade
bone remodeling
cardiac epithelial to mesenchymal transition
negative regulation of cell death
replicative senescence
oxidative stress-induced premature senescence
biological_process
multicellular organism development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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