Proteintech

XAB2 Polyclonal Antibody

FIGURE: 1 / 4

XAB2 Antibody (10637-1-AP) in WB

HeLa cells were subjected to SDS PAGE followed by western blot with 10637-1-AP (XAB2 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

XAB2 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

10637-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 3 publications 3 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

XAB2 Fusion Protein Ag0999 (530-855 aa encoded by BC007208)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.21 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: EHKYFEESF KAYERGISLF KWPNVSDIWS TYLTKFIARY GGRKLERARD LFEQALDGCP PKYAKTLYLL YAQLEEEWGL ARHAMAVYER ATRAVEPAQQ YDMFNIYIKR AAEIYGVTHT RGIYQKAIEV LSDEHAREMC LRFADMECKL GEIDRARAIY SFCSQICDPR TTGAFWQTWK DFEVRHGNED TIKEMLRIRR SVQATYNTQV NFMASQMLKV SGSATGTVSD LAPGQSGMDD MKLLEQRAEQ LAAEAERDQP LRAQSKILFV RSDASREELA ELAQQVNPEE IQLGEDEDED EMDLEPNEVR LEQQSVPAAV FGSLKED (530-855 aa encoded by BC007208 )

Target Information

A novel protein designated XAB2 (XPA-binding protein 2) interacts with XPA, a factor central to both nucleotide excision repair subpathways. Data suggests that XAB2 is a novel component involved in transcription-coupled repair and transcription.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence.

Nucleic acids research

Hou S,Qu D,Li Y,Zhu B,Liang D,Wei X,Tang W,Zhang Q,Hao J,Guo W,Wang W,Zhao S,Wang Q,Azam S,Khan M,Zhao H,Zhang L,Lei H

Thu Sep 05 00:00:00 UTC 2019

XAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE.

Cell death & disease

Hou S,Li N,Zhang Q,Li H,Wei X,Hao T,Li Y,Azam S,Liu C,Cheng W,Jin B,Liu Q,Li M,Lei H

Thu Oct 13 00:00:00 UTC 2016

XAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE.

Cell death & disease

Hou S,Li N,Zhang Q,Li H,Wei X,Hao T,Li Y,Azam S,Liu C,Cheng W,Jin B,Liu Q,Li M,Lei H

Thu Oct 13 00:00:00 UTC 2016

XAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE.

Cell death & disease

Hou S,Li N,Zhang Q,Li H,Wei X,Hao T,Li Y,Azam S,Liu C,Cheng W,Jin B,Liu Q,Li M,Lei H

Thu Oct 13 00:00:00 UTC 2016

XAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE.

Cell death & disease

Hou S,Li N,Zhang Q,Li H,Wei X,Hao T,Li Y,Azam S,Liu C,Cheng W,Jin B,Liu Q,Li M,Lei H

Thu Oct 13 00:00:00 UTC 2016

Evidence that a consensus element found in naturally intronless mRNAs promotes mRNA export.

Nucleic acids research

Lei H,Zhai B,Yin S,Gygi S,Reed R

Fri Feb 01 00:00:00 UTC 2013

Evidence that a consensus element found in naturally intronless mRNAs promotes mRNA export.

Nucleic acids research

Lei H,Zhai B,Yin S,Gygi S,Reed R

Fri Feb 01 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: crn-related protein kim1; DKFZp762C1015; HCNP protein; Pre-mRNA-splicing factor SYF1; Protein HCNP; SYF1 homolog, RNA splicing factor; SYF1 pre-mRNA-splicing factor; XPA-binding protein 2

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Gene Aliases: HCNP; HCRN; KIAA1177; NTC90; PP3898; SYF1; XAB2

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UniProt ID: (Human) Q9HCS7

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Entrez Gene ID: (Human) 56949

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Function(s)

protein binding

Process(es)

generation of catalytic spliceosome for first transesterification step mRNA splicing, via spliceosome blastocyst development transcription-coupled nucleotide-excision repair transcription, DNA-templated cerebral cortex development

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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XAB2 Polyclonal Antibody

XAB2 Antibody (10637-1-AP) in WB

Product Details

10637-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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