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Immunogen sequence: PTPDQKREDD QGAAEIQVPD LEADLQ
Highest antigen sequence identity to the following orthologs: Mouse - 46%, Rat - 42%.
This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in normal testis, and in Ewing's sarcoma, rhabdomyosarcoma, a breast cancer and a germ cell tumor. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cancer/testis antigen 12.2; cancer/testis antigen family 12, member 2; CT12.2; G antigen family D member 3; X antigen family member 2; X antigen family, member 2; X antigen family, member 2B; XAGE-2
Gene Aliases: CT12.2; GAGED3; XAGE-2; XAGE2; XAGE2B
UniProt ID: (Human) Q96GT9
Entrez Gene ID: (Human) 9502
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