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Recommended positive controls: IMR32, U87-MG.
Predicted reactivity: Mouse (97%), Rat (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Exp6; Exportin-6; Ran-binding protein 20
Gene Aliases: EXP6; KIAA0370; RANBP20; XPO6
UniProt ID: (Human) Q96QU8
Entrez Gene ID: (Human) 23214
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