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Immunogen sequence: RPSPDVKAEL FELLFRTLHH NWRYFFKSTV LASVQRGIAE EQMENEPQFS AIMQAFGQSF LQPDIHLFKQ NLFYLETLNT KQKLYHKK
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Exp6; Exportin-6; Ran-binding protein 20
Gene Aliases: EXP6; KIAA0370; RANBP20; XPO6
UniProt ID: (Human) Q96QU8
Entrez Gene ID: (Human) 23214
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