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Invitrogen
XPOT Polyclonal Antibody
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FIGURE: 1 / 1
XPOT Antibody (PA5-88317) in WB
Western blot analysis of XPOT in extracts of various cell lines. Samples were incubated with XPOT Polyclonal antibody (Product # PA5-88317) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-88317
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human XPOT (NP_0091662)
Conjugate
Form
Liquid
Concentration
0.85 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2804824
Product Specific Information
Immunogen sequence: MDEQALLGLN PNADSDFRQR ALAYFEQLKI SPDAWQVCAE ALAQRTYSDD HVKFFCFQVL EHQVKYKYSE LTTVQQQLIR ETLISWLQAQ MLNPQPEKTF IRNKAAQVFA LLFVTEYLTK WPKFFFDILS VVDLNPRGVD LYLRILMAID SELVDRDVVH TSEEARRNTL IKDTMREQCI PNLVESWYQI LQNYQFTNSE; Positive Samples: B-cell, Mouse brain, Mouse kidney, Mouse liver, Rat kidney; Cellular Location: Cytoplasm, Nucleus
Target Information
XPOT is a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Exportin(tRNA); exportin, tRNA (nuclear export receptor for tRNAs); Exportin-T; tRNA exportin
Gene Aliases: 1110004L07Rik; 3110065H13Rik; AI452076; C79645; EXPORTIN-T; XPO3; XPOT
UniProt ID: (Human) O43592
Entrez Gene ID: (Human) 11260, (Mouse) 73192, (Rat) 314879
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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