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Product Details
9939-MSM2-P1ABX
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
PCRP-RBM8A-1B4
Immunogen
Recombinant full-length human RBM8A protein
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Binder of OVCA1-1; BOV-1; BOV1; BOV1A; BOV1B; BOV1C; ribonucleoprotein RBM8; Ribonucleoprotein RBM8A; RNA binding motif protein 8B; rna-binding; RNA-binding motif protein 8A; RNA-binding protein 8A; RNA-binding protein Y14
Gene Aliases: BOV-1A; BOV-1B; BOV-1C; C1DELq21.1; DEL1q21.1; HSPC114; MDS014; RBM8; RBM8A; RBM8B; TAR; Y14; ZNRP; ZRNP1
UniProt ID: (Human) Q9Y5S9
Entrez Gene ID: (Human) 9939
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
regulation of alternative mRNA splicing, via spliceosome
mRNA splicing, via spliceosome
termination of RNA polymerase II transcription
RNA export from nucleus
mRNA export from nucleus
regulation of translation
mRNA 3'-end processing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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