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Invitrogen
YAF2 Polyclonal Antibody
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Product Details
PA5-55446
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human YAF2. Recombinant protein control fragment (Product #RP-89463).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2649713
Product Specific Information
Immunogen sequence: AFKCMMCDVR KGTSTRKPRP VSQLVAQQVT QQFVPPTQSK KEKKDKVEKE KSEKETTSKK NSHKKTRPRL KNVDRSSAQH LEVTVGDLTV IITDFKEKTK SPPASSAASA DQHSQSGSSS DNTERGMSRS SS
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 90%.
Target Information
The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC41856; YY1-associated factor 2
Gene Aliases: YAF2
UniProt ID: (Human) Q8IY57
Entrez Gene ID: (Human) 10138
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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