Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MGRIFLDHI GGTRLFSCAN CDTILTNRSE LISTRFTGAT GRAFLFNKVV NLQYSEVQDR VMLTGRHMVR DVSCKNCNSK LGWIYEFATE DSQRYKEGRV ILERALVRES EGFEEHVPSD NS (1-121 aa encoded by BC000836)
YPEL5 (yippee-like 5) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL5 is expressed at the nucleus and centrosome during interphase; during mitosis, it localizes to the spindle poles, mitotic spindle, and spindle midzone during mitosis. Finally, during cytokinesis, YPEL5 is localized to the midbody. It is associated with the Ran Binding Protein in the Microtubule organizing center (RanBPM) and a related protein RanBP10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Protein yippee-like 5; yippee protein homolog; yippee-like 5
Gene Aliases: 2310076K21Rik; CGI-127; YPEL5
UniProt ID: (Human) P62699, (Mouse) P62700
Entrez Gene ID: (Human) 51646, (Rat) 298792, (Mouse) 383295
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