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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • YTHDF2 Antibodies

          Proteintech

          YTHDF2 Polyclonal Antibody

          257 References
          View all (14) YTHDF2 antibodies

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          Datasheet
          Protocols
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          Datasheet
          Protocols
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          Cite YTHDF2 Polyclonal Antibody

          • Antibody Testing Data (13)
          YTHDF2 Antibody in Immunocytochemistry (ICC/IF)
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          YTHDF2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 13

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          YTHDF2 Antibody (24744-1-AP) in ICC/IF

          Immunofluorescent analysis of (-20°C Ethanol) fixed U2OS cells using YTHDF2 antibody (Product # 24744-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          YTHDF2 Antibody in Immunocytochemistry (ICC/IF)
          YTHDF2 Antibody in Immunocytochemistry (ICC/IF)
          YTHDF2 Antibody in Immunocytochemistry (ICC/IF)
          YTHDF2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          YTHDF2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          YTHDF2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          YTHDF2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          YTHDF2 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          YTHDF2 Antibody in Western Blot (WB)
          YTHDF2 Antibody in Western Blot (WB)
          YTHDF2 Antibody in Western Blot (WB)
          YTHDF2 Antibody in Western Blot (WB)
          YTHDF2 Antibody in Immunoprecipitation (IP)

          Product Details

          24744-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:5,000-1:50,000
          View 159 publications 159 publications

          Immunohistochemistry (IHC)

          -
          View 13 publications 13 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          View 25 publications 25 publications

          Flow Cytometry (Flow)

          -
          View 1 publication 1 publication

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 10 publications 10 publications

          ChIP assay (ChIP)

          -
          View 1 publication 1 publication

          RNA Immunoprecipitation (RIP)

          -
          View 43 publications 43 publications

          Miscellaneous PubMed (MISC)

          -
          View 1 publication 1 publication

          Not applicable (N/A)

          -
          View 4 publications 4 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse, Pig, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          YTHDF2 Fusion Protein Ag5922 (339-565 aa encoded by BC002559)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.25 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: LSVQQQAAQ PTRWVAPRNR GSGFGHNGVD GNGVGQSQAG SGSTPSEPHP VLEKLRSINN YNPKDFDWNL KHGRVFIIKS YSEDDIHRSI KYNIWCSTEH GNKRLDAAYR SMNGKGPVYL LFSVNGSGHF CGVAEMKSAV DYNTCAGVWS QDKWKGRFDV RWIFVKDVPN SQLRHIRLEN NENKPVTNSR DTQEVPLEKA KQVLKIIASY KHTTSIFDDF SHYEKRQE (339-565 aa encoded by BC002559)

          Target Information

          Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation. Also acts as a promoter of cap-independent mRNA translation following heat shock stress: upon stress, relocalizes to the nucleus and specifically binds mRNAs with some m6A methylation mark at their 5'-UTR, protecting demethylation of mRNAs by FTO, thereby promoting cap-independent mRNA translation.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: 9430020E02Rik; CLL-associated antigen KW-14; DF2; High-glucose-regulated protein 8; Renal carcinoma antigen NY-REN-2; YTH domain family 2; YTH domain family protein 2; YTH domain family, member 2; YTH domain-containing family protein 2; YTH N(6)-methyladenosine RNA binding protein 2

          View more View less

          Gene Aliases: 9430020E02Rik; CAHL; HGRG8; NY-REN-2; YTHDF2

          View more View less

          UniProt ID: (Human) Q9Y5A9, (Mouse) Q91YT7

          View more View less

          Entrez Gene ID: (Human) 51441, (Mouse) 213541, (Rat) 313053

          View more View less

          Function(s)
          protein binding poly(A) RNA binding N6-methyladenosine-containing RNA binding RNA binding
          Process(es)
          regulation of mRNA stability humoral immune response positive regulation of cap-independent translational initiation
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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