Proteintech

YTHDF3 Polyclonal Antibody

YTHDF3 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 8

YTHDF3 Antibody (25537-1-AP) in ICC/IF

Immunofluorescent analysis of A549 cells using 25537-1-AP (YTHDF3-specific antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

Product Image Gallery

Product Details

25537-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 49 publications 49 publications

Immunohistochemistry (IHC)

View 5 publications 5 publications

Immunocytochemistry (ICC/IF)

1:20-1:200

View 6 publications 6 publications

Immunoprecipitation (IP)

View 1 publication 1 publication

RNA Immunoprecipitation (RIP)

View 10 publications 10 publications

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

YTHDF3-specific Fusion Protein Ag22374 (284-351 aa encoded by BC052970)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.14 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Product # 25537-1-AP specifically reacts with YTHDF3 protein.

Immunogen sequence: SVVKAPPTQ PVLPPQTIIQ QPQPLIQPPP LVQSQLPQQQ PQPPQPQQQQ GPQPQAQPHQ VQPQQQQLQ (284-351 aa encoded by BC052970)

Target Information

This gene encodes a member of the YTH (YT521-B homology) domain protein family. The YTH domain is common in eukaryotes, is often found in the middle of the protein sequence, and may function in binding to RNA. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Pseudorabies virus exploits N⁶-methyladenosine modification to promote viral replication.

Frontiers in microbiology

Yu PL,Wu R,Cao SJ,Wen YP,Huang XB,Zhao S,Lang YF,Zhao Q,Lin JC,Du SY,Yu SM,Yan QG

Fri Feb 24 00:00:00 UTC 2023

YTHDF2 Is Downregulated in Response to Host Shutoff Induced by DNA Virus Infection and Regulates Interferon-Stimulated Gene Expression.

Journal of virology

Hesser CR,Walsh D

Thu Mar 30 00:00:00 UTC 2023

Regulators of proteostasis are translationally repressed in fibroblasts from patients with sporadic and LRRK2-G2019S Parkinson's disease.

NPJ Parkinson's disease

Flinkman D,Hong Y,Gnjatovic J,Deshpande P,Ortutay Z,Peltonen S,Kaasinen V,James P,Coffey E

Mon Feb 06 00:00:00 UTC 2023

m⁶A-modification of cyclin D1 and c-myc IRESs in glioblastoma controls ITAF activity and resistance to mTOR inhibition.

Cancer letters

Benavides-Serrato A,Saunders JT,Kumar S,Holmes B,Benavides KE,Bashir MT,Nishimura RN,Gera J

Sun May 28 00:00:00 UTC 2023

m⁶A-modification of cyclin D1 and c-myc IRESs in glioblastoma controls ITAF activity and resistance to mTOR inhibition.

Cancer letters

Benavides-Serrato A,Saunders JT,Kumar S,Holmes B,Benavides KE,Bashir MT,Nishimura RN,Gera J

Sun May 28 00:00:00 UTC 2023

Polychlorinated biphenyls alter hepatic m6A mRNA methylation in a mouse model of environmental liver disease.

Environmental research

Petri BJ,Piell KM,Wahlang B,Head KZ,Andreeva K,Rouchka EC,Cave MC,Klinge CM

Sun Jan 01 00:00:00 UTC 2023

Newcastle disease virus activates methylation-related enzymes to reprogram m⁶A methylation in infected cells.

Veterinary microbiology

Yuan W,Hou Y,Wang Q,Lv T,Ren J,Fan L,Cai J,Xiang B,Lin Q,Liao M,Ding C,Chen L,Ren T

Thu Jun 01 00:00:00 UTC 2023

N⁶-methyladenosine mediates Nrf2 protein expression involved in PM2.5-induced pulmonary fibrosis.

Ecotoxicology and environmental safety

Ji D,Hu C,Ning J,Ying X,Zhang H,Zhang B,Liu B,Liu Q,Ji W,Zhang R

Sat Apr 01 00:00:00 UTC 2023

m⁶A reader YTHDF3 is associated with clinical prognosis, related RNA signatures and immunosuppression in gastric cancer.

Cellular signalling

Yu Y,Meng LL,Chen XY,Fan HN,Chen M,Zhang J,Zhu JS

Tue Aug 01 00:00:00 UTC 2023

m⁶A reader YTHDF3 is associated with clinical prognosis, related RNA signatures and immunosuppression in gastric cancer.

Cellular signalling

Yu Y,Meng LL,Chen XY,Fan HN,Chen M,Zhang J,Zhu JS

Tue Aug 01 00:00:00 UTC 2023

Comprehensive analysis of m6A methylation modification in chronic spinal cord injury in mice.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Li C,Zhao J,Qin T,Jin Y,Duan C,Wu T,Romani MD,Cao Y,Lu H,Hu J

Thu Jun 01 00:00:00 UTC 2023

Comprehensive analysis of m6A methylation modification in chronic spinal cord injury in mice.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Li C,Zhao J,Qin T,Jin Y,Duan C,Wu T,Romani MD,Cao Y,Lu H,Hu J

Thu Jun 01 00:00:00 UTC 2023

Adipocyte YTH N(6)-methyladenosine RNA-binding protein 1 protects against obesity by promoting white adipose tissue beiging in male mice.

Nature communications

Yan S,Zhou X,Wu C,Gao Y,Qian Y,Hou J,Xie R,Han B,Chen Z,Wei S,Gao X

Mon Mar 13 00:00:00 UTC 2023

Epitranscriptic regulation of HRAS by N⁶-methyladenosine drives tumor progression.

Proceedings of the National Academy of Sciences of the United States of America

Pan Y,Gu Y,Liu T,Zhang Q,Yang F,Duan L,Cheng S,Zhu X,Xi Y,Chang X,Ye Q,Gao S

Tue Apr 04 00:00:00 UTC 2023

Epitranscriptic regulation of HRAS by N⁶-methyladenosine drives tumor progression.

Proceedings of the National Academy of Sciences of the United States of America

Pan Y,Gu Y,Liu T,Zhang Q,Yang F,Duan L,Cheng S,Zhu X,Xi Y,Chang X,Ye Q,Gao S

Tue Apr 04 00:00:00 UTC 2023

N⁶-methyladenosine reader YTHDF3 contributes to the aerobic glycolysis of osteosarcoma through stabilizing PGK1 stability.

Journal of cancer research and clinical oncology

Liu D,Li Z,Zhang K,Lu D,Zhou D,Meng Y

Sat Jul 01 00:00:00 UTC 2023

N⁶-methyladenosine reader YTHDF3 contributes to the aerobic glycolysis of osteosarcoma through stabilizing PGK1 stability.

Journal of cancer research and clinical oncology

Liu D,Li Z,Zhang K,Lu D,Zhou D,Meng Y

Sat Jul 01 00:00:00 UTC 2023

Involvement of METTL3 in arsenite-induced skin lesions by targeting the SOCS3/STAT3/Krt signaling pathway.

Environmental pollution (Barking, Essex : 1987)

Yang F,Zhang A

Sun Jan 01 00:00:00 UTC 2023

N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis.

Genes & diseases

Peng WX,Liu F,Jiang JH,Yuan H,Zhang Z,Yang L,Mo YY

Wed Mar 01 00:00:00 UTC 2023

METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.

Journal of experimental & clinical cancer research : CR

Wei W,Zhang ZY,Shi B,Cai Y,Zhang HS,Sun CL,Fei YF,Zhong W,Zhang S,Wang C,He B,Jiang GM,Wang H

Tue Jun 20 00:00:00 UTC 2023

Integrated Clinical and Prognostic Analysis of the m⁶A RNA Methylation Regulator YTHDF3 in Pan-Cancer and its Correlation with Cancer Cell Proliferation.

Journal of Cancer

Cao L,Zeng B,Wang Y,Wang X,Qin Y,Zhang C,Wu M,Wang J,Zhang X,Ma L

Wed Jan 11 00:00:00 UTC 2023

Integrated Clinical and Prognostic Analysis of the m⁶A RNA Methylation Regulator YTHDF3 in Pan-Cancer and its Correlation with Cancer Cell Proliferation.

Journal of Cancer

Cao L,Zeng B,Wang Y,Wang X,Qin Y,Zhang C,Wu M,Wang J,Zhang X,Ma L

Wed Jan 11 00:00:00 UTC 2023

Integrated Clinical and Prognostic Analysis of the m⁶A RNA Methylation Regulator YTHDF3 in Pan-Cancer and its Correlation with Cancer Cell Proliferation.

Journal of Cancer

Cao L,Zeng B,Wang Y,Wang X,Qin Y,Zhang C,Wu M,Wang J,Zhang X,Ma L

Wed Jan 11 00:00:00 UTC 2023

m⁶A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress.

Cell reports

Wang L,Zhan G,Maimaitiyiming Y,Su Y,Lin S,Liu J,Su K,Lin J,Shen S,He W,Wang F,Chen J,Sun S,Xue Y,Gu J,Chen X,Zhang J,Zhang L,Wang Q,Chang KJ,Chiou SH,Björklund M,Naranmandura H,Cheng X,Hsu CH

Tue Oct 25 00:00:00 UTC 2022

MiR-30e-3p inhibits gastric cancer development by negatively regulating THO complex 2 and PI3K/AKT/mTOR signaling.

World journal of gastrointestinal oncology

Gu XJ,Li YJ,Wang F,Ye T

Tue Nov 15 00:00:00 UTC 2022

Dynamic Alteration Profile and New Role of RNA m6A Methylation in Replicative and H₂O₂-Induced Premature Senescence of Human Embryonic Lung Fibroblasts.

International journal of molecular sciences

Wu F,Zhang L,Lai C,Peng X,Yu S,Zhou C,Zhang B,Zhang W

Wed Aug 17 00:00:00 UTC 2022

Dynamic Alteration Profile and New Role of RNA m6A Methylation in Replicative and H₂O₂-Induced Premature Senescence of Human Embryonic Lung Fibroblasts.

International journal of molecular sciences

Wu F,Zhang L,Lai C,Peng X,Yu S,Zhou C,Zhang B,Zhang W

Wed Aug 17 00:00:00 UTC 2022

YTHDF3 Facilitates eIF2AK2 and eIF3A Recruitment on mRNAs to Regulate Translational Processes in Oxaliplatin-Resistant Colorectal Cancer.

ACS chemical biology

Zhao Y,Zhao H,Zhang D,Quan Q,Ge Y,Li L,Guo L

Fri Jul 15 00:00:00 UTC 2022

YTHDC1 regulates distinct post-integration steps of HIV-1 replication and is important for viral infectivity.

Retrovirology

N'Da Konan S,Ségéral E,Bejjani F,Bendoumou M,Ait Said M,Gallois-Montbrun S,Emiliani S

Mon Jan 31 00:00:00 UTC 2022

m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-β-induced epithelial-mesenchymal transition of lung cancer cells.

The Journal of biological chemistry

Suphakhong K,Terashima M,Wanna-Udom S,Takatsuka R,Ishimura A,Takino T,Suzuki T

Tue Nov 01 00:00:00 UTC 2022

Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.

Journal of clinical laboratory analysis

Li Z,Xu Q,Huangfu N,Chen X,Zhu J

Sat Jan 01 00:00:00 UTC 2022

Combination of high-fat diet and cadmium impairs testicular spermatogenesis in an m6A-YTHDF2-dependent manner.

Environmental pollution (Barking, Essex : 1987)

Xiong YW,Tan LL,Zhang J,Zhu HL,Zheng XM,Chang W,Gao L,Wei T,Xu DX,Wang H

Tue Nov 15 00:00:00 UTC 2022

N6-methyladenosine of Socs1 modulates macrophage inflammatory response in different stiffness environments.

International journal of biological sciences

Hu Z,Li Y,Yuan W,Jin L,Leung WK,Zhang C,Yang Y

Fri Oct 21 00:00:00 UTC 2022

RNA m⁶A Alterations Induced by Biomineralization Nanoparticles: A Proof-of-Concept Study of Epitranscriptomics for Nanotoxicity Evaluation.

Nanoscale research letters

Pan J,Wang J,Fang K,Hou W,Li B,Zhao J,Ma X

Sat Feb 05 00:00:00 UTC 2022

Novel stress granule-like structures are induced via a paracrine mechanism during viral infection.

Journal of cell science

Iadevaia V,Burke JM,Eke L,Moller-Levet C,Parker R,Locker N

Tue Feb 15 00:00:00 UTC 2022

Novel stress granule-like structures are induced via a paracrine mechanism during viral infection.

Journal of cell science

Iadevaia V,Burke JM,Eke L,Moller-Levet C,Parker R,Locker N

Tue Feb 15 00:00:00 UTC 2022

Fusobacterium nucleatum reduces METTL3-mediated m⁶A modification and contributes to colorectal cancer metastasis.

Nature communications

Chen S,Zhang L,Li M,Zhang Y,Sun M,Wang L,Lin J,Cui Y,Chen Q,Jin C,Li X,Wang B,Chen H,Zhou T,Wang L,Hsu CH,Zhuo W

Thu Mar 10 00:00:00 UTC 2022

Matr3 reshapes m6A modification complex to alleviate macrophage inflammation during atherosclerosis.

Clinical immunology (Orlando, Fla.)

Sun Z,Chen W,Wang Z,Wang S,Zan J,Zheng L,Zhao W

Thu Dec 01 00:00:00 UTC 2022

Matr3 reshapes m6A modification complex to alleviate macrophage inflammation during atherosclerosis.

Clinical immunology (Orlando, Fla.)

Sun Z,Chen W,Wang Z,Wang S,Zan J,Zheng L,Zhao W

Thu Dec 01 00:00:00 UTC 2022

The expression of m6A enzymes in the hippocampus of diabetic cognitive impairment mice and the possible improvement of YTHDF1.

Brain research

Li M,Zhong X,Zhao Z,Zeng Z,Yuan Q,Xiao X,Zu X,Liu J

Tue Feb 15 00:00:00 UTC 2022

Downregulation of circ-ZNF609 Promotes Heart Repair by Modulating RNA N⁶-Methyladenosine-Modified Yap Expression.

Research (Washington, D.C.)

Wang L,Yu P,Wang J,Xu G,Wang T,Feng J,Bei Y,Xu J,Wang H,Das S,Xiao J

Sat Jul 16 00:00:00 UTC 2022

Downregulation of circ-ZNF609 Promotes Heart Repair by Modulating RNA N⁶-Methyladenosine-Modified Yap Expression.

Research (Washington, D.C.)

Wang L,Yu P,Wang J,Xu G,Wang T,Feng J,Bei Y,Xu J,Wang H,Das S,Xiao J

Sat Jul 16 00:00:00 UTC 2022

The RNA m6A reader YTHDF2 controls NK cell antitumor and antiviral immunity.

The Journal of experimental medicine

Ma S,Yan J,Barr T,Zhang J,Chen Z,Wang LS,Sun JC,Chen J,Caligiuri MA,Yu J

Mon Aug 02 00:00:00 UTC 2021

METTL3-dependent RNA m⁶A dysregulation contributes to neurodegeneration in Alzheimer's disease through aberrant cell cycle events.

Molecular neurodegeneration

Zhao F,Xu Y,Gao S,Qin L,Austria Q,Siedlak SL,Pajdzik K,Dai Q,He C,Wang W,O'Donnell JM,Tang B,Zhu X

Thu Sep 30 00:00:00 UTC 2021

METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N⁶-methyladenosine-dependent YTHDF binding.

Nature communications

Wang W,Shao F,Yang X,Wang J,Zhu R,Yang Y,Zhao G,Guo D,Sun Y,Wang J,Xue Q,Gao S,Gao Y,He J,Lu Z

Mon Jun 21 00:00:00 UTC 2021

METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N⁶-methyladenosine-dependent YTHDF binding.

Nature communications

Wang W,Shao F,Yang X,Wang J,Zhu R,Yang Y,Zhao G,Guo D,Sun Y,Wang J,Xue Q,Gao S,Gao Y,He J,Lu Z

Mon Jun 21 00:00:00 UTC 2021

GR-mediated transcriptional regulation of m⁶A metabolic genes contributes to diet-induced fatty liver in hens.

Journal of animal science and biotechnology

Feng Y,Li Y,Jiang W,Hu Y,Jia Y,Zhao R

Tue Dec 07 00:00:00 UTC 2021

Stabilization of UCA1 by N6-methyladenosine RNA methylation modification promotes colorectal cancer progression.

Cancer cell international

He RZ,Jiang J,Hu X,Lei M,Li J,Luo W,Duan L,Hu Z,Mo YY,Luo DX,Peng WX

Mon Nov 22 00:00:00 UTC 2021

Enterovirus 2A^pro Cleavage of the YTHDF m⁶A Readers Implicates YTHDF3 as a Mediator of Type I Interferon-Driven JAK/STAT Signaling.

mBio

Kastan JP,Tremblay MW,Brown MC,Trimarco JD,Dobrikova EY,Dobrikov MI,Gromeier M

Tue Apr 13 00:00:00 UTC 2021

m⁶A modification regulates lung fibroblast-to-myofibroblast transition through modulating KCNH6 mRNA translation.

Molecular therapy : the journal of the American Society of Gene Therapy

Zhang JX,Huang PJ,Wang DP,Yang WY,Lu J,Zhu Y,Meng XX,Wu X,Lin QH,Lv H,Xie H,Wang RL

Wed Dec 01 00:00:00 UTC 2021

Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase.

Nucleic acids research

Xia Z,Tang M,Ma J,Zhang H,Gimple RC,Prager BC,Tang H,Sun C,Liu F,Lin P,Mei Y,Du R,Rich JN,Xie Q

Wed Jul 21 00:00:00 UTC 2021

Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase.

Nucleic acids research

Xia Z,Tang M,Ma J,Zhang H,Gimple RC,Prager BC,Tang H,Sun C,Liu F,Lin P,Mei Y,Du R,Rich JN,Xie Q

Wed Jul 21 00:00:00 UTC 2021

TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4.

Cell death & disease

Wang H,Wei W,Zhang ZY,Liu Y,Shi B,Zhong W,Zhang HS,Fang X,Sun CL,Wang JB,Liu LX

Fri Dec 17 00:00:00 UTC 2021

TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4.

Cell death & disease

Wang H,Wei W,Zhang ZY,Liu Y,Shi B,Zhong W,Zhang HS,Fang X,Sun CL,Wang JB,Liu LX

Fri Dec 17 00:00:00 UTC 2021

N6-methyladenosine regulates ATM expression and downstream signaling.

Journal of Cancer

Zhang X,Liu P,Zheng X,Wang J,Peng Q,Li Z,Wei L,Liu C,Wu Y,Wen Y,Yan Q,Ma J

Sat Aug 17 00:00:00 UTC 2024

Differential roles of YTHDF1 and YTHDF3 in embryonic stem cell-derived cardiomyocyte differentiation.

RNA biology

Wang S,Zhang J,Wu X,Lin X,Liu XM,Zhou J

Wed Sep 01 00:00:00 UTC 2021

KDM5B promotes self-renewal of hepatocellular carcinoma cells through the microRNA-448-mediated YTHDF3/ITGA6 axis.

Journal of cellular and molecular medicine

Guo JC,Liu Z,Yang YJ,Guo M,Zhang JQ,Zheng JF

Thu Jul 01 00:00:00 UTC 2021

KDM5B promotes self-renewal of hepatocellular carcinoma cells through the microRNA-448-mediated YTHDF3/ITGA6 axis.

Journal of cellular and molecular medicine

Guo JC,Liu Z,Yang YJ,Guo M,Zhang JQ,Zheng JF

Thu Jul 01 00:00:00 UTC 2021

MYC promotes cancer progression by modulating m⁶ A modifications to suppress target gene translation.

EMBO reports

Wu G,Suo C,Yang Y,Shen S,Sun L,Li ST,Zhou Y,Yang D,Wang Y,Cai Y,Wang N,Zhang H,Yang YG,Cao J,Gao P

Wed Mar 03 00:00:00 UTC 2021

Oncogenic AURKA-enhanced N⁶-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.

Cell research

Peng F,Xu J,Cui B,Liang Q,Zeng S,He B,Zou H,Li M,Zhao H,Meng Y,Chen J,Liu B,Lv S,Chu P,An F,Wang Z,Huang J,Zhan Y,Liao Y,Lu J,Xu L,Zhang J,Sun Z,Li Z,Wang F,Lam EW,Liu Q

Mon Mar 01 00:00:00 UTC 2021

m⁶A-binding YTHDF proteins promote stress granule formation.

Nature chemical biology

Fu Y,Zhuang X

Tue Sep 01 00:00:00 UTC 2020

Expression and Prognostic Significance of m6A-Related Genes in Lung Adenocarcinoma.

Medical science monitor : international medical journal of experimental and clinical research

Zhang Y,Liu X,Liu L,Li J,Hu Q,Sun R

Sat Feb 22 00:00:00 UTC 2020

Modulation of circRNA Metabolism by m⁶A Modification.

Cell reports

Di Timoteo G,Dattilo D,Centrón-Broco A,Colantoni A,Guarnacci M,Rossi F,Incarnato D,Oliviero S,Fatica A,Morlando M,Bozzoni I

Tue May 12 00:00:00 UTC 2020

METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice.

Nature communications

Wang Y,Gao M,Zhu F,Li X,Yang Y,Yan Q,Jia L,Xie L,Chen Z

Fri Apr 03 00:00:00 UTC 2020

YTH domain family 2 promotes lung cancer cell growth by facilitating 6-phosphogluconate dehydrogenase mRNA translation.

Carcinogenesis

Sheng H,Li Z,Su S,Sun W,Zhang X,Li L,Li J,Liu S,Lu B,Zhang S,Shan C

Fri Jul 10 00:00:00 UTC 2020

Musashi-1 promotes cancer stem cell properties of glioblastoma cells via upregulation of YTHDF1.

Cancer cell international

Yarmishyn AA,Yang YP,Lu KH,Chen YC,Chien Y,Chou SJ,Tsai PH,Ma HI,Chien CS,Chen MT,Wang ML

Mon Dec 14 00:00:00 UTC 2020

HIV protease cleaves the antiviral m6A reader protein YTHDF3 in the viral particle.

PLoS pathogens

Jurczyszak D,Zhang W,Terry SN,Kehrer T,Bermúdez González MC,McGregor E,Mulder LCF,Eckwahl MJ,Pan T,Simon V

Sat Feb 01 00:00:00 UTC 2020

Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation.

PLoS pathogens

Brocard M,Iadevaia V,Klein P,Hall B,Lewis G,Lu J,Burke J,Willcocks MM,Parker R,Goodfellow IG,Ruggieri A,Locker N

Wed Jan 01 00:00:00 UTC 2020

N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication.

Nucleic acids research

Hao H,Hao S,Chen H,Chen Z,Zhang Y,Wang J,Wang H,Zhang B,Qiu J,Deng F,Guan W

Thu Jan 10 00:00:00 UTC 2019

N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication.

Nucleic acids research

Hao H,Hao S,Chen H,Chen Z,Zhang Y,Wang J,Wang H,Zhang B,Qiu J,Deng F,Guan W

Thu Jan 10 00:00:00 UTC 2019

Dynamic m⁶A mRNA methylation reveals the role of METTL3-m⁶A-CDCP1 signaling axis in chemical carcinogenesis.

Oncogene

Yang F,Jin H,Que B,Chao Y,Zhang H,Ying X,Zhou Z,Yuan Z,Su J,Wu B,Zhang W,Qi D,Chen D,Min W,Lin S,Ji W

Sat Jun 01 00:00:00 UTC 2019

m⁶A facilitates hippocampus-dependent learning and memory through YTHDF1.

Nature

Shi H,Zhang X,Weng YL,Lu Z,Liu Y,Lu Z,Li J,Hao P,Zhang Y,Zhang F,Wu Y,Delgado JY,Su Y,Patel MJ,Cao X,Shen B,Huang X,Ming GL,Zhuang X,Song H,He C,Zhou T

Thu Nov 01 00:00:00 UTC 2018

m⁶A facilitates hippocampus-dependent learning and memory through YTHDF1.

Nature

Shi H,Zhang X,Weng YL,Lu Z,Liu Y,Lu Z,Li J,Hao P,Zhang Y,Zhang F,Wu Y,Delgado JY,Su Y,Patel MJ,Cao X,Shen B,Huang X,Ming GL,Zhuang X,Song H,He C,Zhou T

Thu Nov 01 00:00:00 UTC 2018

RNA m⁶ A modification enzymes shape innate responses to DNA by regulating interferon β.

Genes & development

Rubio RM,Depledge DP,Bianco C,Thompson L,Mohr I

Sat Dec 01 00:00:00 UTC 2018

RNA m⁶ A modification enzymes shape innate responses to DNA by regulating interferon β.

Genes & development

Rubio RM,Depledge DP,Bianco C,Thompson L,Mohr I

Sat Dec 01 00:00:00 UTC 2018

Bioinformatics

Protein Aliases: DF3; YTH domain family protein 3; YTH domain family, member 3; YTH domain-containing family protein 3; YTH N(6)-methyladenosine RNA binding protein 3

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Gene Aliases: 9130022A11Rik; YTHDF3

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UniProt ID: (Human) Q7Z739, (Mouse) Q8BYK6

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Entrez Gene ID: (Human) 253943, (Mouse) 229096

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Function(s)

protein binding poly(A) RNA binding N6-methyladenosine-containing RNA binding RNA binding

Process(es)

biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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YTHDF3 Polyclonal Antibody

YTHDF3 Antibody (25537-1-AP) in ICC/IF

Product Details

25537-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

RNA Immunoprecipitation (RIP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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