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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • YY1 Antibodies

          Proteintech

          YY1 Polyclonal Antibody

          34 References
          View all (32) YY1 antibodies

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          Datasheet
          Protocols
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          Datasheet
          Protocols
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          Cite YY1 Polyclonal Antibody

          • Antibody Testing Data (8)
          YY1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          YY1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          YY1 Antibody (22156-1-AP) in ICC/IF

          Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using (Product # 22156-1-AP) (YY1 antibody) at dilution of 1:100 and CoraLite488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          YY1 Antibody in Immunocytochemistry (ICC/IF)
          YY1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          YY1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          YY1 Antibody in Western Blot (WB)
          YY1 Antibody in Western Blot (WB)
          YY1 Antibody in Western Blot (WB)
          YY1 Antibody in Western Blot (WB)
          YY1 Antibody in Immunoprecipitation (IP)

          Product Details

          22156-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 20 publications 20 publications

          Immunohistochemistry (IHC)

          -
          View 2 publications 2 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:100
          View 3 publications 3 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 2 publications 2 publications

          ChIP assay (ChIP)

          -
          View 7 publications 7 publications
          Product Specifications

          Species Reactivity

          Human, Mouse

          Published species

          Human, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          YY1 Fusion Protein Ag17792 (1-414 aa encoded by BC037308)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.3 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          The open reading frame of the human YY1 cDNA encodes a protein of 414 amino acids with a predicted molecular weight of 44 kDa. However, YY1 migrates on SDS gels as a 65-68 kDa protein, probably due to the structure of the protein. It is a ubiquitously expressed transcription factor with fundamental roles in embryogenesis, differentiation, replication, and proliferation. This is a rabbit polyclonal antibody raised against full length YY1 of human origin.

          Immunogen sequence: MASGDTLYI ATDGSEMPAE IVELHEIEVE TIPVETIETT VVGEEEEEDD DDEDGGGGDH GGGGGHGHAG HHHHHHHHHH HPPMIALQPL VTDDPTQVHH HQEVILVQTR EEVVGGDDSD GLRAEDGFED QILIPVPAPA GGDDDYIEQT LVTVAAAGKS GGGGSSSSGG GRVKKGGGKK SGKKSYLSGG AGAAGGGGAD PGNKKWEQKQ VQIKTLEGEF SVTMWSSDEK KDIDHETVVE EQIIGENSPP DYSEYMTGKK LPPGGIPGID LSDPKQLAEF ARMKPRKIKE DDAPRTIACP HKGCTKMFRD NSAMRKHLHT HGPRVHVCAE CGKAFVESSK LKRHQLVHTG EKPFQCTFEG CGKRFSLDFN LRTHVRIHTG DRPYVCPFDG CNKKFAQSTN LKSHILTHAK AKNNQ (1-414 aa encoded by BC037308)

          Target Information

          YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Delta transcription factor; INO80 complex subunit S; NF-E1; Transcriptional repressor protein YY1; UCR-motif DNA-binding protein; UCRBP transcription factor; Yin and yang 1; Yin and Yang 1 protein; Yin Yang 1; YY-1

          View more View less

          Gene Aliases: AW488674; DELTA; INO80S; NF-E1; UCRBP; YIN-YANG-1; YY1

          View more View less

          UniProt ID: (Human) P25490, (Mouse) Q00899

          View more View less

          Entrez Gene ID: (Human) 7528, (Mouse) 22632

          View more View less

          Function(s)
          four-way junction DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding enhancer sequence-specific DNA binding DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity transcription corepressor activity RNA binding protein binding zinc ion binding transcription regulatory region DNA binding SMAD binding nucleic acid binding histone deacetylase binding sequence-specific DNA binding metal ion binding
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter double-strand break repair via homologous recombination transcription, DNA-templated regulation of transcription from RNA polymerase II promoter cellular response to DNA damage stimulus spermatogenesis response to UV-C negative regulation of gene expression cell differentiation cellular response to UV DNA repair DNA recombination regulation of transcription, DNA-templated transcription from RNA polymerase II promoter RNA localization anterior/posterior pattern specification positive regulation of gene expression positive regulation of transcription from RNA polymerase II promoter camera-type eye morphogenesis chromosome organization cellular response to interleukin-1
          It has to be done as per old AB suggested Products section.
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