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NeoBiotechnologies
YY1 (Transcription Factor) Monoclonal Antibody (YY1/5436)
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Product Details
7528-MSM3-P1ABX
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2, kappa
Class
Monoclonal
Type
Antibody
Clone
YY1/5436
Immunogen
His-tagged YY1 protein
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
Positive Control: Human kidney tonsil or cervix carcinoma tissues
Cellular Location: Nucleus matrix. Associated with the nuclear matrix.
Target Information
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Delta transcription factor; INO80 complex subunit S; NF-E1; Transcriptional repressor protein YY1; Yin and yang 1; Yin and Yang 1 protein; YY-1
Gene Aliases: DELTA; INO80S; NF-E1; UCRBP; YIN-YANG-1; YY1
UniProt ID: (Human) P25490
Entrez Gene ID: (Human) 7528
four-way junction DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
enhancer sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
transcription corepressor activity
RNA binding
protein binding
zinc ion binding
transcription regulatory region DNA binding
SMAD binding
negative regulation of transcription from RNA polymerase II promoter
double-strand break repair via homologous recombination
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
spermatogenesis
response to UV-C
negative regulation of gene expression
cell differentiation
cellular response to UV
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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