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Proteintech
ZBTB1 Polyclonal Antibody
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Product Details
26287-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ZBTB1 Fusion Protein Ag23492 (1-357 aa encoded by BC050719)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAKPSHSSY VLQQLNNQRE WGFLCDCCIA IDDIYFQAHK AVLAACSSYF RMFFMNHQHS TAQLNLSNMK ISAECFDLIL QFMYLGKIMT APSSFEQFKV AMNYLQLYNV PDCLEDIQDA DCSSSKCSSS ASSKQNSKMI FGVRMYEDTV ARNGNEANRW CAEPSSTVNT PHNREADEES LQLGNFPEPL FDVCKKSSVS KLSTPKERVS RRFGRSFTCD SCGFGFSCEK LLDEHVLTCT NRHLYQNTRS YHRIVDIRDG KDSNIKAEFG EKDSSKTFSA QTDKYRGDTS QAADDSASTT GSRKSSTVES EIASEEKSRA AERKRIIIKM EPEDTPTDEL KDFNIIKVTD KDCNESTD (1-357 aa encoded by BC050719)
Target Information
ZBTB1 acts as a transcriptional repressor. Represses cAMP-responsive element (CRE)-mediated transcriptional activation. In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis. Plays a key role in the transcriptional regulation of T lymphocyte development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Zinc finger and BTB domain-containing protein 1
Gene Aliases: KIAA0997; ZBTB1; ZNF909
UniProt ID: (Human) Q9Y2K1
Entrez Gene ID: (Human) 22890
negative regulation of transcription from RNA polymerase II promoter
positive regulation of T cell mediated immunity
DNA repair
chromatin remodeling
cellular response to DNA damage stimulus
translesion synthesis
B cell differentiation
positive regulation of natural killer cell differentiation
T cell differentiation in thymus
cellular response to UV
mRNA transcription from RNA polymerase II promoter
innate immune response
positive regulation of T cell differentiation
thymus development
protein homooligomerization
positive regulation of pro-T cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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