Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 1
ZBTB17 Antibody (PA5-120300) in WB
Western blot analysis of ZBTB17 in extracts of various cell lines. Samples were incubated with ZBTB17 Polyclonal antibody (Product # PA5-120300) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-120300
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 121-360 of human ZBTB17 (NP_003434.2).
Conjugate
Form
Liquid
Concentration
0.74 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2913872
Product Specific Information
Positive test controls include: B Cell, HeLa. The target is usually found in the following locations: Nucleus.
Immunogen sequence: PGGNAEALAT EGGDKRAKEE KVATSTLSRL EQAGRSTPIG PSRDLKEERG GQAQSAASGA EQTEKADAPR EPPPVELKPD PTSGMAAAEA EAALSESSEQ EMEVEPARKG EEEQKEQEEQ EEEGAGPAEV KEEGSQLENG EAPEENENEE SAGTDSGQEL GSEARGLRSG TYGDRTESKA YGSVIHKCED CGKEFTHTGN FKRHIRIHTG EKPFSCRECS KAFSDPAACK AHEKTHSPLK
Target Information
Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: LP-1; Miz-1; Myc-interacting zinc finger protein 1; Myc-interacting Zn finger protein-1; Polyomavirus late initiator promoter-binding protein; Zfp-100; Zinc finger and BTB domain-containing protein 17; Zinc finger protein 100; Zinc finger protein 151; zinc finger protein 151 (pHZ-67); Zinc finger protein 60; Zinc finger protein Z13
Gene Aliases: AA589413; Lp-1; MIZ-1; MIZ1; mZ13; pHZ-67; ZBTB17; Zfp100; ZNF151; ZNF60
UniProt ID: (Human) Q13105, (Mouse) Q60821
Entrez Gene ID: (Human) 7709, (Rat) 313666, (Mouse) 22642
gastrulation with mouth forming second
transcription, DNA-templated
ectoderm development
IRE1-mediated unfolded protein response
negative regulation of cell cycle
positive regulation of transcription, DNA-templated
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
regulation of transcription, DNA-templated
multicellular organism development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support