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ZBTB6 Antibody (PA5-62922) in IHC (P)
Immunohistochemical analysis of ZBTB6 in human tonsil using ZBTB6 Polyclonal Antibody (Product # PA5-62922) shows strong nuclear positivity in a subset of non-germinal center cells. Germinal center cells exhibited moderate cytoplasmic and nuclear staining in a fraction of cells.
Product Details
PA5-62922
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ZBTB6. Recombinant protein control fragment (Product #RP-101569).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2649782
Product Specific Information
Immunogen sequence: CTEPLSKYLE IDLSMKNNNQ HTDLCQSSDP DVKNEDENSD KDCEIIEISE DSPVNIDFHV K
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 89%.
Target Information
The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB6, also known as ZNF482, is highly expressed in brain. While little is known about ZBTB6, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB family member, ZBTB5, also acts as a transcriptional repressor, and can interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, suggesting that ZBTB6 may also act as a transcriptional repressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Zinc finger and BTB domain-containing protein 6; Zinc finger protein 482; Zinc finger protein with interaction domain
Gene Aliases: ZBTB6; ZID; ZNF482
UniProt ID: (Human) Q15916
Entrez Gene ID: (Human) 10773
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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