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This target displays homology in the following species: Cow: 92%; Guinea Pig: 86%; Horse: 91%; Human: 100%; Mouse: 100%; Rat: 100%
Required for the export of polyadenylated mRNAs from the nucleus (PubMed:19364924). Enhances ACVR1B-induced SMAD-dependent transcription. Binds to single-stranded DNA but not to double-stranded DNA in vitro. Involved in RNA cleavage. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Smad-interacting CPSF-like factor; Zinc finger CCCH domain-containing protein 3; zinc finger CCCH type domain containing 3
Gene Aliases: BC049953; Kiaa0150; Smicl; Zc3h3; Zc3hdc3; Zfp623
UniProt ID: (Mouse) Q8CHP0
Entrez Gene ID: (Mouse) 223642
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