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Invitrogen
ZDHHC18 Polyclonal Antibody
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ZDHHC18 Antibody (PA5-116614) in IHC (P)
Immunohistochemistry analysis of ZDHHC18 in paraffin-embedded human lung cancer. Samples were incubated with ZDHHC18 Polyclonal antibody (Product # PA5-116614) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-116614
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 301-388 of human ZDHHC18 (NP_1156591)
Conjugate
Form
Liquid
Concentration
0.99 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2901245
Product Specific Information
Positive Samples: Raji, HeLa, Mouse brain, Rat brain
Immunogen sequence: YLVASNLTTN EDIKGSWSSK RGGEASVNPY SHKSIITNCC AVLCGPLPPS LIDRRGFVQS DTVLPSPIRS DEPACRAKPD ASMVGGHP
Target Information
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DHHC domain-containing cysteine-rich protein 18; DHHC-18; membrane-associated DHHC18 zinc finger protein; Palmitoyltransferase ZDHHC18; Zinc finger DHHC domain-containing protein 18; zinc finger, DHHC domain containing 18; zinc finger, DHHC-type containing 18
Gene Aliases: DHHC-18; DHHC18; ZDHHC18
UniProt ID: (Human) Q9NUE0, (Mouse) Q5Y5T2, (Rat) Q2TGJ1
Entrez Gene ID: (Human) 84243, (Mouse) 503610, (Rat) 362613
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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