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Immunogen sequence: EPGGDIQQEA LGDQLQLVEE EFALQGVNAL KEEACPGDTQ LEEGRKEPEA PGEMPAPAVH LASPQAESTA LPPCELETT
Highest antigen sequence identity to the following orthologs: Mouse - 60%, Rat - 61%.
This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: zinc finger and AT hook domain containing; Zinc finger gene in AITD susceptibility region; zinc finger gene in autoimmune thyroid disease; Zinc finger protein 406; Zinc finger protein ZFAT; zinc-finger gene in AITD susceptibility region
Gene Aliases: AITD3; KIAA1485; ZFAT; ZFAT1; ZNF406
UniProt ID: (Human) Q9P243
Entrez Gene ID: (Human) 57623
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