Invitrogen

ZFP36L1 Polyclonal Antibody

View all (15) ZFP36L1 antibodies

Promotion

View available promotion(s)

Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-27445

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:3,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human TIS11B. The exact sequence is proprietary.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

6.34 mg/mL

Purification

Protein A

Storage buffer

0.1M tris glycine, pH 7, with 10% glycerol

Contains

0.01% thimerosal

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2544921

Product Specific Information

Recommended positive controls: 293T, A431, Jurkat, Raji.

Predicted reactivity: Mouse (98%), Rat (98%), Chicken (89%), Bovine (98%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: Butyrate response factor 1; early response factor Berg36; EGF-response factor 1; ERF-1; mRNA decay activator protein ZFP36L1; TPA-induced sequence 11b; ZFP36 ring finger protein-like 1; ZFP36-like 1; zinc finger protein 36, C3H type-like 1; Zinc finger protein 36, C3H1 type-like 1; zinc finger protein, C3H type, 36-like 1

View more View less

Gene Aliases: BERG36; BRF1; cMG1; ERF-1; ERF1; RNF162B; TIS11B; ZFP36L1

View more View less

UniProt ID: (Human) Q07352

View more View less

Entrez Gene ID: (Human) 677

View more View less

Function(s)
DNA binding transcription factor activity, sequence-specific DNA binding mRNA binding mRNA 3'-UTR binding protein binding mRNA 3'-UTR AU-rich region binding poly(A) RNA binding metal ion binding 14-3-3 protein binding
Process(es)
MAPK cascade nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay vasculogenesis proepicardium development regulation of transcription, DNA-templated apoptotic process heart development cell proliferation response to wounding regulation of gene expression regulation of keratinocyte proliferation phosphatidylinositol 3-kinase signaling neural tube development nuclear-transcribed mRNA catabolic process, deadenylation-independent decay regulation of mRNA 3'-end processing cellular response to insulin stimulus T cell differentiation in thymus multicellular organism growth p38MAPK cascade regulation of mRNA stability protein kinase B signaling cellular response to fibroblast growth factor stimulus positive regulation of fat cell differentiation regulation of keratinocyte differentiation negative regulation of erythrocyte differentiation positive regulation of monocyte differentiation regulation of myoblast differentiation mesendoderm development mRNA transport chorio-allantoic fusion spongiotrophoblast layer development 3'-UTR-mediated mRNA destabilization ERK1 and ERK2 cascade cellular response to cAMP cellular response to tumor necrosis factor cellular response to epidermal growth factor stimulus cellular response to peptide hormone stimulus cellular response to glucocorticoid stimulus cellular response to hypoxia cellular response to salt stress cellular response to transforming growth factor beta stimulus regulation of stem cell proliferation cellular response to raffinose positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay regulation of keratinocyte apoptotic process positive regulation of intracellular mRNA localization cellular response to phorbol 13-acetate 12-myristate
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support