Proteintech

ZFYVE16 Polyclonal Antibody

ZFYVE16 Antibody in Immunocytochemistry (ICC/IF)

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ZFYVE16 Antibody (13118-2-AP) in ICC/IF

Immunofluorescent analysis of HeLa cells using 13118-2-AP (ZFYVE16 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

ZFYVE16 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

ZFYVE16 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

13118-2-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Zebrafish

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ZFYVE16 Fusion Protein Ag3811 (1-306 aa encoded by BC032227)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.15 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MDSYFKAAV SDLDKLLDDF EQNPDEQDYL QDVQNAYDSN HCSVSSELAS SQRTSLLPKD QECVNSCASS ETSYGTNESS LNEKTLKGLT SIQNEKNVTG LDLLSSVDGG TSDEIQPLYM GRCSKPICDL ISDMGNLVHA TNSEEDIKKL LPDDFKSNAD SLIGLDLSSV SDTPCVSSTD HDSDTVREQQ NDTSSELQNR EIGGIKELGI KVDTTLSDSY NYSGTENLKD KKIFNQLESI VDFNMSSALT RQSSKMFHAK DKLQHKSQPC GLLKDVGLVK EEVDVAVITA AECLKEEGKT SALTCSL (1-306 aa encoded by BC032227)

Target Information

The ZFYVE16 gene encodes endofin, an endosomal protein implicated in regulating membrane trafficking. It is characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain positioned in the middle of the molecule.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.

iScience

Kazan JM,Desrochers G,Martin CE,Jeong H,Kharitidi D,Apaja PM,Roldan A,St Denis N,Gingras AC,Lukacs GL,Pause A

Fri Nov 19 00:00:00 UTC 2021

Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP.

Structure (London, England : 1993)

Gahloth D,Levy C,Walker L,Wunderley L,Mould AP,Taylor S,Woodman P,Tabernero L

Wed Jul 05 00:00:00 UTC 2017

Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP.

Structure (London, England : 1993)

Gahloth D,Levy C,Walker L,Wunderley L,Mould AP,Taylor S,Woodman P,Tabernero L

Wed Jul 05 00:00:00 UTC 2017

The Lowe syndrome protein OCRL1 is required for endocytosis in the zebrafish pronephric tubule.

PLoS genetics

Oltrabella F,Pietka G,Ramirez IB,Mironov A,Starborg T,Drummond IA,Hinchliffe KA,Lowe M

Wed Apr 01 00:00:00 UTC 2015

The Lowe syndrome protein OCRL1 is required for endocytosis in the zebrafish pronephric tubule.

PLoS genetics

Oltrabella F,Pietka G,Ramirez IB,Mironov A,Starborg T,Drummond IA,Hinchliffe KA,Lowe M

Wed Apr 01 00:00:00 UTC 2015

SARA is dispensable for functional TGF-β signaling.

FEBS letters

Bakkebø M,Huse K,Hilden VI,Forfang L,Myklebust JH,Smeland EB,Oksvold MP

Fri Sep 21 00:00:00 UTC 2012

SARA is dispensable for functional TGF-β signaling.

FEBS letters

Bakkebø M,Huse K,Hilden VI,Forfang L,Myklebust JH,Smeland EB,Oksvold MP

Fri Sep 21 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: Endofin; Endosomal-associated FYVE domain protein; Endosome-associated FYVE domain protein; endosome-associated FYVE-domain protein; protein phosphatase 1, regulatory subunit 69; Zinc finger FYVE domain-containing protein 16; zinc finger, FYVE domain containing 16

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Gene Aliases: AI035632; B130024H06Rik; B130031L15; KIAA0305; mKIAA0305; PPP1R69; RGD1564784; ZFYVE16

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UniProt ID: (Human) Q7Z3T8, (Mouse) Q80U44

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Entrez Gene ID: (Human) 9765, (Mouse) 218441, (Rat) 499508

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Function(s)

protein binding 1-phosphatidylinositol binding phosphatidylinositol-3,4,5-trisphosphate binding protein transporter activity metal ion binding

Process(es)

protein targeting to lysosome signal transduction vesicle organization endosomal transport regulation of endocytosis BMP signaling pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ZFYVE16 Polyclonal Antibody

ZFYVE16 Antibody (13118-2-AP) in ICC/IF

Product Details

13118-2-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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