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Proteintech
ZFYVE19 Polyclonal Antibody
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Product Details
23163-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ZFYVE19 Fusion Protein Ag19593 (123-471 aa encoded by BC015738)
Conjugate
Form
Liquid
Concentration
0.65 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VCKQCHEVL TRGSSANASK WSPPQNYKKR VAALEAKQKP STSQSQGLTR QDQMIAERLA RLRQENKPKL VPSQAEIEAR LAALKDERQG SIPSTQEMEA RLAALQGRVL PSQTPQPAHH TPDTRTQAQQ TQDLLTQLAA EVAIDESWKG GGPAASLQND LNQGGPGSTN SKRQANWSLE EEKSRLLAEA ALELREENTR QERILALAKR LAMLRGQDPE RVTLQDYRLP DSDDDEDEET AIQRVLQQLT EEAALDEASG FNIPAEQASR PWTQPRGAEP EAQDVDPRPE AEEEELPWCC ICNEDATLRC AGCDGDLFCA RCFREGHDAF ELKEHQTSAY SPPRAGQEH (123-471 aa encoded by BC015738)
Target Information
Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Abscission/NoCut checkpoint regulator; ANCHR; MLL partner containing FYVE domain; Zinc finger FYVE domain-containing protein 19; zinc finger, FYVE domain containing 19
Gene Aliases: ANCHR; MPFYVE; ZFYVE19
UniProt ID: (Human) Q96K21
Entrez Gene ID: (Human) 84936
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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