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Proteintech
ZGPAT Polyclonal Antibody
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Product Details
23203-1-AP
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ZGPAT Fusion Protein Ag19620 (173-511 aa encoded by BC032612)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: THKSLKPCP FFLEGKCRFK ENCRFSHGQV VSLDELRPFQ DPDLSSLQAG SACLAKHQDG LWHAARITDV DNGYYTVKFD SLLLREAVVE GDGILPPLRT EATESDSDSD GTGDSSYARV VGSDAVDSGT CSSAFAGWEV HTRGIGSRLL TKMGYEFGKG LGRHAEGRVE PIHAVVLPRG KSLDQCVETL QKQTRVGKAG TNKPPRCRGR GARPGGRPAP RNVFDFLNEK LQGQAPGALE AGAAPAGRRS KDMYHASKSA KRALSLRLFQ TEEKIERTQR DIRSIQEALA RNAGRHSVAS AQLQEKLAGA QRQLGQLRAQ EAGLQQEQRK ADTHKKMTEF (173-511 aa encoded by BC032612)
Target Information
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G patch domain-containing protein 6; Zinc finger and G patch domain-containing protein; Zinc finger CCCH domain-containing protein 9; zinc finger CCCH-type with G patch domain; Zinc finger CCCH-type with G patch domain-containing protein; zinc finger, CCCH-type with G patch domain; zinc finger, CCCH-type with G-patch domain
Gene Aliases: 1500006I01Rik; BC021513; GPATC6; GPATCH6; KIAA1847; ZC3H9; ZC3HDC9; ZGPAT; ZIP
UniProt ID: (Human) Q8N5A5, (Mouse) Q8VDM1
Entrez Gene ID: (Human) 84619, (Mouse) 229007
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
metal ion binding
nucleic acid binding
DNA binding
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
negative regulation of epidermal growth factor-activated receptor activity
negative regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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