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Invitrogen
ZIC Pan Polyclonal Antibody
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Product Details
PA5-68610
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the N terminal region of human ZIC Pan
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2688572
Product Specific Information
This target displays homology in the following species: Dog: 100%; Guinea Pig: 86%; Human: 100%; Mouse: 100%; Pig: 92%; Rabbit: 100%; Zebrafish: 79%
Target Information
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: heterotaxy 1; Zic family member 1 (odd-paired homolog, Drosophila); Zic family member 2 (odd-paired homolog, Drosophila); Zic family member 3 (odd-paired homolog, Drosophila); Zic family member 5 (odd-paired homolog, Drosophila); zinc family member 4 protein HZIC4; zinc family member 5 protein; Zinc finger protein 201; Zinc finger protein 203; Zinc finger protein of the cerebellum 1; Zinc finger protein of the cerebellum 2; Zinc finger protein of the cerebellum 3; Zinc finger protein of the cerebellum 4; Zinc finger protein of the cerebellum 5; Zinc finger protein ZIC 1; Zinc finger protein ZIC 2; Zinc finger protein ZIC 3; Zinc finger protein ZIC 4; Zinc finger protein ZIC 5
Gene Aliases: CRS6; HPE5; HTX; HTX1; VACTERLX; ZIC; ZIC1; ZIC2; ZIC3; ZIC4; ZIC5; ZNF201; ZNF203
UniProt ID: (Human) Q15915, (Human) O95409, (Human) O60481, (Human) Q8N9L1, (Human) Q96T25
Entrez Gene ID: (Human) 7545, (Human) 7546, (Human) 7547, (Human) 84107, (Human) 85416
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
metal ion binding
DNA binding
chromatin DNA binding
protein binding
sequence-specific DNA binding
heart looping
transcription from RNA polymerase II promoter
determination of left/right symmetry
anterior/posterior pattern specification
cell differentiation
lung development
somatic stem cell population maintenance
determination of pancreatic left/right asymmetry
determination of left/right asymmetry in nervous system
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
determination of digestive tract left/right asymmetry
determination of liver left/right asymmetry
pattern specification process
brain development
adult walking behavior
regulation of smoothened signaling pathway
spinal cord development
positive regulation of protein import into nucleus
inner ear morphogenesis
transcription, DNA-templated
visual perception
negative regulation of transcription, DNA-templated
positive regulation of sequence-specific DNA binding transcription factor activity
nervous system development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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