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Product Details
19429-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ZIP7 Fusion Protein Ag13762 (237-384 aa encoded by BC000645)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Dual bands of 50 kDa and 56 kDa detected by this antibody may represent the native and phosphorylated forms of ZIP7, respectively.
Immunogen sequence: VRHVKGGHG HSHGHGHAHS HTRGSHGHGR QERSTKEKQS SEEEEKETRG VQKRRGGSTV PKDGPVRPQN AEEEKRGLDL RVSGYLNLAA DLAHNFTDGL AIGASFRGGR GLGILTTMTV LLHEVPHEVG DFAILVQSGC SKKQAMRLQ (237-384 aa encoded by BC000645)
Target Information
The zinc transporter ZIP7, also known as SLC39A7, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP7 was initially identified while characterizing genes in the major histocompatibility complex on chromosome 17. ZIP7 mRNA is abundantly and widely expressed and the protein localizes to the Golgi apparatus. It functions to transport intracellular zinc from the Golgi apparatus to the cytoplasm of the cell. ZIP7 expression is expressed by zinc. ZIP7 has been suggested to act a hub for tyrosine kinase activation and may thus be a potential therapeutic target for diseases such as cancer where prevention of tyrosine kinase activation would be advantageous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DADB-100D22.3; H2-K region expressed gene 4; Histidine-rich membrane protein; Histidine-rich membrane protein Ke4; HLA class II region expressed gene KE4; Ke4 gene; Ke4 gene, mouse, human homolog of; Really interesting new gene 5 protein; RT1 class I, locus Ke4; RT1 region expressed gene KE4; solute carrier family 39 (zinc transporter), member 7; Solute carrier family 39 member 7; Zinc transporter SLC39A7; ZIP7; Zrt-, Irt-like protein 7
Gene Aliases: AA408174; AI117660; AL024048; D6S115E; D6S2244E; H-2Ke4; H2-KE4; HKE4; Ke-4; KE4; RING5; RT1-Ke4; Rt1Ke4; SLC39A7; ZIP7
UniProt ID: (Human) Q92504, (Mouse) Q31125, (Rat) Q6MGB4
Entrez Gene ID: (Human) 7922, (Mouse) 14977, (Rat) 294281
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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