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Product Details
12847-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ZMPSTE24 Fusion Protein Ag3949 (225-475 aa encoded by BC037283)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KFTPLPEGK LKEEIEVMAK SIDFPLTKVY VVEGSKRSSH SNAYFYGFFK NKRIVLFDTL LEEYSVLNKD IQEDSGMEPR NEEEGNSEEI KAKVKNKKQG CKNEEVLAVL GHELGHWKLG HTVKNIIISQ MNSFLCFFLF AVLIGRKELF AAFGFYDSQP TLIGLLIIFQ FIFSPYNEVL SFCLTVLSRR FEFQADAFAK KLGKAKDLYS ALIKLNKDNL GFPVSDWLFS MWHYSHPPLL ERLQALKTMK QH (225-475 aa encoded by BC037283)
Target Information
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAAX prenyl protease 1 homolog; FACE-1; Farnesylated proteins-converting enzyme 1; FLJ14968; Prenyl protein-specific endoprotease 1; zinc metallopeptidase STE24 homolog; Zinc metalloproteinase Ste24 homolog
Gene Aliases: FACE-1; FACE1; HGPS; PRO1; STE24; Ste24p; ZMPSTE24
UniProt ID: (Human) O75844
Entrez Gene ID: (Human) 10269
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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