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Invitrogen
ZMYND8 Polyclonal Antibody
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ZMYND8 Antibody (PA5-97151) in WB
Western blot analysis of RACK7 in extracts of various cell lines. Samples were incubated with RACK7 Polyclonal antibody (Product # PA5-97151) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Product Details
PA5-97151
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 959-1188 of human ZMYND8 (NP_8988681)
Conjugate
Form
Liquid
Concentration
4.3 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2808953
Product Specific Information
Immunogen sequence: LELTMAEMRQ SLEQERDRLI AEVKKQLELE KQQAVDETKK KQWCANCKKE AIFYCCWNTS YCDYPCQQAH WPEHMKSCTQ SATAPQQEAD AEVNTETLNK SSQGSSSSTQ SAPSETASAS KEKETSAEKS KESGSTLDLS GSRETPSSIL LGSNQGSVSK RCDKQPAYAP TTTDHQPHPN YPAQKYHSRS NKSSWSSSDE KRGSTRSDHN TSTSTKSLLP KESRLDTFWD; Positive Samples: U-87 MG, LO2, MCF-7, A375
Target Information
The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CTCL tumor antigen se14-3; CTCL-associated antigen se14-3; Cutaneous T-cell lymphoma-associated antigen se14-3; MYND-type zinc finger-containing chromatin reader ZMYND8; predicted protein of HQ2893; Protein kinase C-binding protein 1; Rack7; Transcription coregulator ZMYND8; Zinc finger MYND domain-containing protein 8; zinc finger, MYND-type containing 8
Gene Aliases: KIAA1125; PRKCBP1; PRO2893; RACK7; ZMYND8
UniProt ID: (Human) Q9ULU4
Entrez Gene ID: (Human) 23613
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
positive regulation of filopodium assembly
positive regulation of dendritic spine development
modulation of excitatory postsynaptic potential
regulation of postsynaptic density protein 95 clustering
positive regulation of dendritic spine maintenance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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