Proteintech

ZNF143 Polyclonal Antibody

FIGURE: 1 / 3

ZNF143 Antibody (16618-1-AP) in WB

Mouse brain tissue were subjected to SDS PAGE followed by western blot with 16618-1-AP (ZNF143 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Product Details

16618-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

View 1 publication 1 publication

ChIP assay (ChIP)

Assay-dependent

View 6 publications 6 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ZNF143 Fusion Protein Ag9914 (283-626 aa encoded by BC020219)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.32 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: KPYRCSEDN CTKSFKTSGD LQKHIRTHTG ERPFKCPFEG CGRSFTTSNI RKVHVRTHTG ERPYYCTEPG CGRAFASATN YKNHVRIHTG EKPYVCTVPG CDKRFTEYSS LYKHHVVHTH SKPYNCNHCG KTYKQISTLV MHKRTAHNDT EPIEEEQEAF FEPPPGQGED VLKGSQITYV TGVEGDDVVS TQVATVTQSG LSQQVTLISQ DGTQHVNISQ ADMQAIGNTI TMVTQDGTPI TVPAHDAVIS SAGTHSVAMV TAEGTEGQQV AIVAQDLAAF HTASSEMGHQ QHSHHLVTTE TRPLTLVATS NGTQIAVQLG EQPSLEEAIR IASRIQQGET PGLDD (283-626 aa encoded by BC020219)

Target Information

Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

FBXO9 Mediates the Cancer-Promoting Effects of ZNF143 by Degrading FBXW7 and Facilitates Drug Resistance in Hepatocellular Carcinoma.

Frontiers in oncology

Wang Z,Chen X,Zhou L,Zhao X,Ge C,Zhao F,Xie H,Chen T,Tian H,Li H,Li J

Tue Jul 19 00:00:00 UTC 2022

FBXO9 Mediates the Cancer-Promoting Effects of ZNF143 by Degrading FBXW7 and Facilitates Drug Resistance in Hepatocellular Carcinoma.

Frontiers in oncology

Wang Z,Chen X,Zhou L,Zhao X,Ge C,Zhao F,Xie H,Chen T,Tian H,Li H,Li J

Tue Jul 19 00:00:00 UTC 2022

The role of ZNF143 overexpression in rat liver cell proliferation.

BMC genomics

Ye B,Shen W,Zhang C,Yu M,Ding X,Yin M,Wang Y,Guo X,Bai G,Lin K,Shi S,Li P,Zhang Y,Yu G,Zhao Z

Sat Jul 02 00:00:00 UTC 2022

The role of ZNF143 overexpression in rat liver cell proliferation.

BMC genomics

Ye B,Shen W,Zhang C,Yu M,Ding X,Yin M,Wang Y,Guo X,Bai G,Lin K,Shi S,Li P,Zhang Y,Yu G,Zhao Z

Sat Jul 02 00:00:00 UTC 2022

The role of ZNF143 overexpression in rat liver cell proliferation.

BMC genomics

Ye B,Shen W,Zhang C,Yu M,Ding X,Yin M,Wang Y,Guo X,Bai G,Lin K,Shi S,Li P,Zhang Y,Yu G,Zhao Z

Sat Jul 02 00:00:00 UTC 2022

Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy.

Nature communications

Chern T,Achilleos A,Tong X,Hill MC,Saltzman AB,Reineke LC,Chaudhury A,Dasgupta SK,Redhead Y,Watkins D,Neilson JR,Thiagarajan P,Green JBA,Malovannaya A,Martin JF,Rosenblatt DS,Poché RA

Mon Jan 10 00:00:00 UTC 2022

ZNF143-Mediated H3K9 Trimethylation Upregulates CDC6 by Activating MDIG in Hepatocellular Carcinoma.

Cancer research

Zhang L,Huo Q,Ge C,Zhao F,Zhou Q,Chen X,Tian H,Chen T,Xie H,Cui Y,Yao M,Li H,Li J

Mon Jun 15 00:00:00 UTC 2020

Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells.

Journal of experimental & clinical cancer research : CR

Song Y,Shao L,Xue Y,Ruan X,Liu X,Yang C,Zheng J,Shen S,Chen J,Li Z,Liu Y

Tue Jun 11 00:00:00 UTC 2019

Maintenance of CTCF- and Transcription Factor-Mediated Interactions from the Gametes to the Early Mouse Embryo.

Molecular cell

Jung YH,Kremsky I,Gold HB,Rowley MJ,Punyawai K,Buonanotte A,Lyu X,Bixler BJ,Chan AWS,Corces VG

Thu Jul 11 00:00:00 UTC 2019

Architectural Proteins and Pluripotency Factors Cooperate to Orchestrate the Transcriptional Response of hESCs to Temperature Stress.

Molecular cell

Lyu X,Rowley MJ,Corces VG

Thu Sep 20 00:00:00 UTC 2018

Architectural Proteins and Pluripotency Factors Cooperate to Orchestrate the Transcriptional Response of hESCs to Temperature Stress.

Molecular cell

Lyu X,Rowley MJ,Corces VG

Thu Sep 20 00:00:00 UTC 2018

Host cell factor-1 recruitment to E2F-bound and cell-cycle-control genes is mediated by THAP11 and ZNF143.

Cell reports

Parker JB,Yin H,Vinckevicius A,Chakravarti D

Thu Nov 06 00:00:00 UTC 2014

Host cell factor-1 recruitment to E2F-bound and cell-cycle-control genes is mediated by THAP11 and ZNF143.

Cell reports

Parker JB,Yin H,Vinckevicius A,Chakravarti D

Thu Nov 06 00:00:00 UTC 2014

Host cell factor-1 recruitment to E2F-bound and cell-cycle-control genes is mediated by THAP11 and ZNF143.

Cell reports

Parker JB,Yin H,Vinckevicius A,Chakravarti D

Thu Nov 06 00:00:00 UTC 2014

Host cell factor-1 recruitment to E2F-bound and cell-cycle-control genes is mediated by THAP11 and ZNF143.

Cell reports

Parker JB,Yin H,Vinckevicius A,Chakravarti D

Thu Nov 06 00:00:00 UTC 2014

Cooperative transcription factor associations discovered using regulatory variation.

Proceedings of the National Academy of Sciences of the United States of America

Karczewski KJ,Tatonetti NP,Landt SG,Yang X,Slifer T,Altman RB,Snyder M

Tue Aug 09 00:00:00 UTC 2011

Cooperative transcription factor associations discovered using regulatory variation.

Proceedings of the National Academy of Sciences of the United States of America

Karczewski KJ,Tatonetti NP,Landt SG,Yang X,Slifer T,Altman RB,Snyder M

Tue Aug 09 00:00:00 UTC 2011

Bioinformatics

Protein Aliases: hStaf; mStaf; selenocysteine tRNA gene transcription activating factor; Selenocysteine tRNA gene transcription-activating factor; SPH-binding factor; transcriptional activator Staf; Zfp-143; Zinc finger protein 143; zinc finger protein 80, related sequence 1

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Gene Aliases: AA959806; AU015869; D7Ertd805e; KRAB14; pHZ-1; SBF; STAF; Zfp143; Zfp79; Zfp80-rs1; ZNF143

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UniProt ID: (Human) P52747, (Mouse) O70230, (Rat) Q5XIU2

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Entrez Gene ID: (Human) 7702, (Mouse) 20841, (Rat) 361627

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Function(s)

DNA binding protein binding metal ion binding nucleic acid binding chromatin binding

Process(es)

transcription, DNA-templated regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of smooth muscle cell proliferation regulation of transcription from RNA polymerase II promoter regulation of transcription from RNA polymerase III promoter transcription from RNA polymerase II promoter transcription from RNA polymerase III promoter snRNA transcription from RNA polymerase II promoter

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ZNF143 Polyclonal Antibody

ZNF143 Antibody (16618-1-AP) in WB

Product Details

16618-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

ChIP assay (ChIP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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