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Proteintech
ZNF488 Polyclonal Antibody
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Product Details
21014-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ZNF488 Fusion Protein Ag15239 (108-340 aa encoded by BC026895)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKDRQVDAQ AQEREHDDPT GQPGAPQLTQ NIPRGPAGSK VFSVWPSGAR SEQRSAFSKP TKRPAERPEL TSVFPAGESA DALGELSGLL NTTDLACWGR LSTPKLLVGD LWNLQALPQN APLCSTFLGA PTLWLEHTQA QVPPPSSSST TSWALLPPTL TSLGLSTQNW CAKCNLSFRL TSDLVFHMRS HHKKEHAGPD PHSQKRREEA LACPVCQEHF RERHHLSRHM TSHS (108-340 aa encoded by B C026895)
Target Information
Transcriptional repressor. Plays a role in oligodendrocyte differentiation, together with OLIG2. Mediates Notch signaling-activated formation of oligodendrocyte precursors. Promotes differentiation of adult neural stem progenitor cells (NSPCs) into mature oligodendrocytes and contributes to remyelination following nerve injury. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Zinc finger protein 488
Gene Aliases: Gm1206; Zfp488; ZNF488
UniProt ID: (Human) Q96MN9, (Mouse) Q5HZG9
Entrez Gene ID: (Human) 118738, (Rat) 290571, (Mouse) 382867
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
oligodendrocyte development
negative regulation of transcription, DNA-templated
positive regulation of oligodendrocyte differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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