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Recommended positive controls: HepG2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The ZNF707 gene, a member of the zinc-finger protein (ZNF) family, encodes a transcription factor that can significantly influence various cellular processes by binding to DNA and regulating gene expression. Located on chromosome 4q32, zinc-finger proteins like ZNF707 are characterized by their zinc-finger motifs, which enable their interaction with specific DNA sequences. Mutations in ZNF707, such as rs4873815-TT, have been implicated in the tumorigenesis and prognosis of ovarian clear cell adenocarcinoma (Ov-CCA), highlighting its clinical significance in cancer research. Research also suggests that missense mutations in ZNF genes can alter protein-DNA interactions, potentially leading to cancer development.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Zinc finger protein 707
Gene Aliases: ZNF707
UniProt ID: (Human) Q96C28
Entrez Gene ID: (Human) 286075
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