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Search Thermo Fisher Scientific
Immunogen sequence: QWEEPWVEDR ERPEFQAVQR GPRPGARKSA DPKRHCDHPA WAHKKTHVRR ERAREGSSFR KGFRLDTDDG Q
Highest antigen sequence identity to the following orthologs: Mouse - 32%, Rat - 32%.
The ZNF707 gene, a member of the zinc-finger protein (ZNF) family, encodes a transcription factor that can significantly influence various cellular processes by binding to DNA and regulating gene expression. Located on chromosome 4q32, zinc-finger proteins like ZNF707 are characterized by their zinc-finger motifs, which enable their interaction with specific DNA sequences. Mutations in ZNF707, such as rs4873815-TT, have been implicated in the tumorigenesis and prognosis of ovarian clear cell adenocarcinoma (Ov-CCA), highlighting its clinical significance in cancer research. Research also suggests that missense mutations in ZNF genes can alter protein-DNA interactions, potentially leading to cancer development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Zinc finger protein 707
Gene Aliases: ZNF707
UniProt ID: (Human) Q96C28
Entrez Gene ID: (Human) 286075
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