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Abnova
ZNF83 Polyclonal Antibody, MaxPab™
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Product Details
H00055769-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ZNF83 (AAH50407.1, 1 a.a. approximately 516 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MHGRKDDAQK QPVKNQLGLN PQSHLPELQL FQAEGKIYKY DHMEKSVNSS SLVSPPQRIS STVKTHISHT YECNFVDSLF TQKEKANIGT EHYKCNERGK AFHQGLHFTI HQIIHTKETQ FKCDICGKIF NKKSNLASHQ RIHTGEKPYK CNECGKVFHN MSHLAQHRRI HTGEKPYKCN ECGKVFNQIS HLAQHQRIHT GEKPYKCNEC GKVFHQISHL AQHRTIHTGE KPYECNKCGK VFSRNSYLVQ HLIIHTGEKP YRCNVCGKVF HHISHLAQHQ RIHTGEKPYK CNECGKVFSH KSSLVNHWRI HTGEKPYKCN ECGKVFSHKS SLVNHWRIHT GEKPYKCNEC GKVFSRNSYL AQHLIIHAGE KPYKCDECDK AFSQNSHLVQ HRRIHTGEKP YKCDECGKVF SQNSYLAYHW RIHTGEKAYK CNECGKVFGL NSSLAHHRKI HTGEKPFKCN ECGKAFSMRS SLTNHHAIHT GEKHFKCNEC GKLFRDNSYL VRHQRFHAGK KSNTCN
Target Information
The ZNF83 gene encodes a zinc-finger protein belonging to a large family of transcription factors that play essential roles in regulating gene expression by interacting with DNA. Located on chromosome 3, ZNF83 is particularly notable for its recurrent mutations in cancer. For instance, the p.E293V missense mutation in ZNF83 has been frequently observed in bladder cancer patients, accounting for 18% of cases, and is associated with poor prognosis. This mutation disrupts the gene's tumor suppressor function, promoting increased tumor growth. Due to its significant role in tumorigenesis, ZNF83 is actively studied in cancer research as a potential biomarker and therapeutic target.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Zinc finger protein 816B; Zinc finger protein 83; Zinc finger protein HPF1
Gene Aliases: HPF1; ZNF816B; ZNF83
UniProt ID: (Human) P51522
Entrez Gene ID: (Human) 55769
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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