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Abnova
ZNHIT2 Polyclonal Antibody, MaxPab™
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Product Details
H00000741-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ZNHIT2 (NP_055020, 1 a.a. approximately 403 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MEPAGPCGFC PAGEVQPARY TCPRCNAPYC SLRCYRTHGT CAENFYRDQV LGELRGCSAP PSRLASALRR LRQQRETEDE PGEAGLSSGP APGGLSGLWE RLAPGEKAAF ERLLSRGEAG RLLPPWRPWW WNRGAGPQLL EELDNAPGSD AAELELAPAR TPPDSVKDAS AAEPAAAERV LGDVPGACTP VVPTRIPAIV SLSRGPVSPL VRFQLPNVLF AYAHTLALYH GGDDALLSDF CATLLGVSGA LGAQQVFASA EEALQAAAHV LEAGEHPPGP LGTRGAMHEV ARILLGEGPT NQKGYTLAAL GDLAQTLGRA RKQAVAREER DHLYRARKKC QFLLAWTNEN EAALTPLALD CARAHQAHAV VAEEVAALTG ELERLWGGPV PPAPRTLIEE LPS
Target Information
The ZNHIT2 gene, located on chromosome 7, encodes a zinc-finger HIT-type containing protein crucial for various cellular processes, such as chromatin remodeling and gene transcription regulation. Knockout studies in mice reveal that ZNHIT2, alongside ZNHIT1, is essential during early development, with deficits leading to embryonic lethality during peri-implantation stages due to reduced proportions of pluripotent inner cell mass cells and aberrant expression of key developmental genes like NANOG and SOX17. This gene's relevance extends to its involvement in protein-protein and protein-nucleic acid interactions that are fundamental in cellular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein FON; Zinc finger HIT domain-containing protein 2; zinc finger, HIT domain containing 2; zinc finger, HIT type 2; zinc finger, HIT-type containing 2
Gene Aliases: C11orf5; FON; ZNHIT2
UniProt ID: (Human) Q9UHR6
Entrez Gene ID: (Human) 741
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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