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Invitrogen
ZNHIT2 Polyclonal Antibody
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Product Details
PA5-29483
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human ZNHIT2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2546959
Product Specific Information
Recommended positive controls: mouse testis.
Predicted reactivity: Bovine (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The ZNHIT2 gene, located on chromosome 7, encodes a zinc-finger HIT-type containing protein crucial for various cellular processes, such as chromatin remodeling and gene transcription regulation. Knockout studies in mice reveal that ZNHIT2, alongside ZNHIT1, is essential during early development, with deficits leading to embryonic lethality during peri-implantation stages due to reduced proportions of pluripotent inner cell mass cells and aberrant expression of key developmental genes like NANOG and SOX17. This gene's relevance extends to its involvement in protein-protein and protein-nucleic acid interactions that are fundamental in cellular functions.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein FON; Zinc finger HIT domain-containing protein 2; zinc finger, HIT domain containing 2; zinc finger, HIT domain containing 2, pseudogene; zinc finger, HIT type 2; zinc finger, HIT-type containing 2
Gene Aliases: C11orf5; FON; ORF6; ZNHIT2; Znhit2-ps
UniProt ID: (Human) Q9UHR6, (Mouse) Q9QY66
Entrez Gene ID: (Human) 741, (Mouse) 29805
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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