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Abnova
ZNRF4 Polyclonal Antibody, MaxPab™
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Product Details
H00148066-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ZNRF4 (NP_859061.2, 1 a.a. approximately 429 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPLCRPEHLM PRASRVPVAA SLPLSHAVIP TQLPSRSGHR PPGRPRRCPK ASCLPPPVGP SSTQTAKRVT MGWPRPGQAL VAVKALLVLS LLQVPAQAVV RAVLEDNSSS VDFADLPALF GVPLAPEGIR GYLMEVKPAN ACHPIEAPRL GNRSLGSIAL IRHYDCTFDL KVLNAQRAGF EAAIVHNVHS DDLVSMTHVY EDLRGQIAIP SVFVSEAASQ DLRVILGCNK SAHALLLPDD PPCHDLGCHP VLTVSWVLGC TLALVVSAFF VLNHLWLWAQ ACCSHRRPVK TSTCQKAQVR TFTWHNDLCA ICLDEYEEGD QLKILPCSHT YHCKCIDPWF SQAPRRSCPV CKQSVAATED SFDSTTYSFR DEDPSLPGHR PPIWAIQVQL RSRRLELLGR ASPHCHCSTT SLEAEYTTVS SAPPEAPGQ
Target Information
E3 ubiquitin-protein ligase that acts as a negative regulator of NOD2 signaling by mediating ubiquitination and degradation of RIPK2. Also catalyzes ubiquitination and proteasomal degradation of CANX within the endoplasmic reticulum. Could have a role in spermatogenesis (By similarity).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase ZNRF4; KOX18; Nixin; RING finger protein 204; RING-type E3 ubiquitin transferase ZNRF4; Zinc/RING finger protein 4; ZNF139; ZNF36
Gene Aliases: RNF204; SPERIZIN; spzn; Ssrzf1; ZNRF4
UniProt ID: (Human) Q8WWF5
Entrez Gene ID: (Human) 148066
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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