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Invitrogen
ZNRF4 Monoclonal Antibody (1A8)
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Product Details
MA5-23082
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1A8
Immunogen
ZNRF4 (NP_859061.2, 108 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1.0 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2606341
Product Specific Information
Peptide Sequence: SSSVDFADLP ALFGVPLAPE GIRGYLMEVK PANACHPIEA PRLGNRSLGS IALIRRYDCT FDL
Target Information
E3 ubiquitin-protein ligase that acts as a negative regulator of NOD2 signaling by mediating ubiquitination and degradation of RIPK2. Also catalyzes ubiquitination and proteasomal degradation of CANX within the endoplasmic reticulum. Could have a role in spermatogenesis (By similarity).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase ZNRF4; KOX18; Nixin; RING finger protein 204; RING-type E3 ubiquitin transferase ZNRF4; Zinc/RING finger protein 4; ZNF139; ZNF36
Gene Aliases: RNF204; SPERIZIN; spzn; Ssrzf1; ZNRF4
UniProt ID: (Human) Q8WWF5
Entrez Gene ID: (Human) 148066
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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