Product References
The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities.
Cell death and differentiation
Iennaco R,Formenti G,Trovesi C,Rossi RL,Zuccato C,Lischetti T,Bocchi VD,Scolz A,Martínez-Labarga C,Rickards O,Pacifico M,Crottini A,Møller AP,Chen RZ,Vogt TF,Pavesi G,Horner DS,Saino N,Cattaneo E
40-2300 was used in Immunocytochemistry to investigate the function and evolution of the physiological CAG tract in the HTT gene. We show that the poly-glutamine (polyQ) tract encoded by CAGs in the huntingtin protein (HTT) is under purifying selection and subjected to stronger selective pressures than CAG-encoded polyQ tracts in other proteins.
Tue Feb 01 00:00:00 UTC 2022
LINC01094/SPI1/CCL7 Axis Promotes Macrophage Accumulation in Lung Adenocarcinoma and Tumor Cell Dissemination.
Journal of immunology research
Wu Z,Bai X,Lu Z,Liu S,Jiang H
40-2300 was used in Western Blotting to reveal that LINC01094 binds to SPI1 to promote its nuclear translocation, which further activates CCL7 transcription by binding to its promoter, leading to M2 macrophage accumulation and dissemination of tumor cells.
Tue Sep 20 00:00:00 UTC 2022
LINC01094/SPI1/CCL7 Axis Promotes Macrophage Accumulation in Lung Adenocarcinoma and Tumor Cell Dissemination.
Journal of immunology research
Wu Z,Bai X,Lu Z,Liu S,Jiang H
40-2300 was used in Western Blotting to reveal that LINC01094 binds to SPI1 to promote its nuclear translocation, which further activates CCL7 transcription by binding to its promoter, leading to M2 macrophage accumulation and dissemination of tumor cells.
Tue Sep 20 00:00:00 UTC 2022
Phaseolus vulgaris extract ameliorates high-fat diet-induced colonic barrier dysfunction and inflammation in mice by regulating peroxisome proliferator-activated receptor expression and butyrate levels.
Frontiers in pharmacology
Avagliano C,De Caro C,Cuozzo M,Liguori FM,La Rana G,Micheli L,Di Cesare Mannelli L,Ghelardini C,Paciello O,Russo R
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Western Blot
Tue Aug 30 00:00:00 UTC 2022
Hydrocephalus in Mice Is Underpinned by Changes in Ependymal Cell Physiology.
Cells
Harkins D,Harvey TJ,Atterton C,Miller I,Currey L,Oishi S,Kasherman M,Davila RA,Harris L,Green K,Piper H,Parton RG,Thor S,Cooper HM,Piper M
40-2300 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to demonstrate a pivotal role for nuclear factor one X (NFIX) in the regulation of cell adhesion within ependymal cells of the lateral ventricles.
Tue Aug 02 00:00:00 UTC 2022
Hydrocephalus in Mice Is Underpinned by Changes in Ependymal Cell Physiology.
Cells
Harkins D,Harvey TJ,Atterton C,Miller I,Currey L,Oishi S,Kasherman M,Davila RA,Harris L,Green K,Piper H,Parton RG,Thor S,Cooper HM,Piper M
40-2300 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to demonstrate a pivotal role for nuclear factor one X (NFIX) in the regulation of cell adhesion within ependymal cells of the lateral ventricles.
Tue Aug 02 00:00:00 UTC 2022
Hydrocephalus in Mice Is Underpinned by Changes in Ependymal Cell Physiology.
Cells
Harkins D,Harvey TJ,Atterton C,Miller I,Currey L,Oishi S,Kasherman M,Davila RA,Harris L,Green K,Piper H,Parton RG,Thor S,Cooper HM,Piper M
40-2300 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to demonstrate a pivotal role for nuclear factor one X (NFIX) in the regulation of cell adhesion within ependymal cells of the lateral ventricles.
Tue Aug 02 00:00:00 UTC 2022
Exacerbated VEGF up-regulation accompanies diabetes-aggravated hemorrhage in mice after experimental cerebral ischemia and delayed reperfusion.
Neural regeneration research
Lai AKW,Ng TC,Hung VKL,Tam KC,Cheung CW,Chung SK,Lo ACY
40-2300 was used in Western Blotting to show that at as early as 2 hours after reperfusion, Ins2Akita/+ mice exhibited rapid development of neurological deficits, increased infarct and hemorrhagic transformation, together with exacerbated down-regulation of tight-junction protein ZO-1 and up-regulation of blood-brain barrier-disrupting matrix metallopeptidase 2 and matrix metallopeptidase 9 when compared with normoglycemic Ins2+/+ mice.
Fri Jul 01 00:00:00 UTC 2022
Exacerbated VEGF up-regulation accompanies diabetes-aggravated hemorrhage in mice after experimental cerebral ischemia and delayed reperfusion.
Neural regeneration research
Lai AKW,Ng TC,Hung VKL,Tam KC,Cheung CW,Chung SK,Lo ACY
40-2300 was used in Western Blotting to show that at as early as 2 hours after reperfusion, Ins2Akita/+ mice exhibited rapid development of neurological deficits, increased infarct and hemorrhagic transformation, together with exacerbated down-regulation of tight-junction protein ZO-1 and up-regulation of blood-brain barrier-disrupting matrix metallopeptidase 2 and matrix metallopeptidase 9 when compared with normoglycemic Ins2+/+ mice.
Fri Jul 01 00:00:00 UTC 2022
The Protective Role of Apelin in the Early Stages of Diabetic Retinopathy.
International journal of molecular sciences
Feng J,Yang W,Luan F,Ma F,Wang Y,Zhang Y,Liu X,Chen L,Hu X,Tao Y
40-2300 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to suggest that apelin can reduce vascular leakage by protecting pericytes, which offers a promising new direction for the early treatment of DR.
Thu Nov 24 00:00:00 UTC 2022
The Protective Role of Apelin in the Early Stages of Diabetic Retinopathy.
International journal of molecular sciences
Feng J,Yang W,Luan F,Ma F,Wang Y,Zhang Y,Liu X,Chen L,Hu X,Tao Y
40-2300 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to suggest that apelin can reduce vascular leakage by protecting pericytes, which offers a promising new direction for the early treatment of DR.
Thu Nov 24 00:00:00 UTC 2022
Possible Toxic Mechanisms of Deoxynivalenol (DON) Exposure to Intestinal Barrier Damage and Dysbiosis of the Gut Microbiota in Laying Hens.
Toxins
Zhai X,Qiu Z,Wang L,Luo Y,He W,Yang J
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Western Blot
Fri Sep 30 00:00:00 UTC 2022
Isolation of Hepatocytes from Liver Tissue by a Novel, Semi-Automated Perfusion Technology.
Biomedicines
Poggel C,Adams T,Janzen R,Hofmann A,Hardt O,Roeb E,Schröder SK,Tag CG,Roderfeld M,Weiskirchen R
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Western Blot
Tue Sep 06 00:00:00 UTC 2022
High level of polarized engraftment of porcine intrahepatic cholangiocyte organoids in decellularized liver scaffolds.
Journal of cellular and molecular medicine
Krüger M,Samsom RA,Oosterhoff LA,van Wolferen ME,Kooistra HS,Geijsen N,Penning LC,Kock LM,Sainz-Arnal P,Baptista PM,Spee B
40-2300 was used in Immunohistochemistry (PFA) to differentiate into hepatocyte- and cholangiocyte-like cells.
Sat Oct 01 00:00:00 UTC 2022
Current diagnostics for chronic enteropathies in dogs.
Veterinary clinical pathology
Allenspach K,Mochel JP
40-2300 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to discuss several novel assays that have the potential to become commercially available such as genetic tests, perinuclear anti-neutrophil cytoplasmic antibodies (pANCA), antibodies against transglutaminase/gliadin, antibodies against E coli OmpC/flagellin, and micro RNAs.
Tue Feb 01 00:00:00 UTC 2022
A medium composition containing normal resting glucose that supports differentiation of primary human airway cells.
Scientific reports
Morgan R,Manfredi C,Easley KF,Watkins LD,Hunt WR,Goudy SL,Sorscher EJ,Koval M,Molina SA
40-2300 was used in Immunocytochemistry to demonstrate that normal glucose containing medium supports differentiation of primary nasal and lung epithelial cells at ALI, is well suited for metabolic studies, and avoids pitfalls associated with exposure to high glucose.
Thu Jan 27 00:00:00 UTC 2022
Sciatic Nerve Intrafascicular Injection Induces Neuropathy by Activating the Matrix Modulators MMP-9 and TIMP-1.
Frontiers in pharmacology
Tseng KY,Wang HC,Cheng KF,Wang YH,Chang LL,Cheng KI
40-2300 was used in Immunohistochemistry-immunofluorescence to investigate whether unintended needle piercing alone, or the intrafascicular nerve injectant could induce neuropathy.
Sat Jul 16 00:00:00 UTC 2022
Increased Mucosal Thrombin is Associated with Crohn's Disease and Causes Inflammatory Damage through Protease-activated Receptors Activation.
Journal of Crohn's & colitis
Motta JP,Palese S,Giorgio C,Chapman K,Denadai-Souza A,Rousset P,Sagnat D,Guiraud L,Edir A,Seguy C,Alric L,Bonnet D,Bournet B,Buscail L,Gilletta C,Buret AG,Wallace JL,Hollenberg MD,Oswald E,Barocelli E,Le Grand S,Le Grand B,Deraison C,Vergnolle N
40-2300 was used in Immunohistochemistry to determine whether and how dysregulated thrombin activity could contribute to local tissue malfunctions associated with Crohn's disease.
Tue May 04 00:00:00 UTC 2021
Ruscogenin attenuated tight junction injury and tumor migration in colorectal liver metastasis mice via regulating TRAP1.
Translational cancer research
Lv Y,Wu X,Chen J,Shao F
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunocytochemistry
Mon Mar 01 00:00:00 UTC 2021
A microfluidic chip carrier including temperature control and perfusion system for long-term cell imaging.
HardwareX
Cantoni F,Werr G,Barbe L,Porras AM,Tenje M
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunocytochemistry
Fri Oct 01 00:00:00 UTC 2021
Bazedoxifene, a Selective Estrogen Receptor Modulator, Promotes Functional Recovery in a Spinal Cord Injury Rat Model.
International journal of molecular sciences
Kim Y,Roh EJ,Joshi HP,Shin HE,Choi H,Kwon SY,Sohn S,Han I
40-2300 was used in Immunocytochemistry to examine the effects of BZA in a rat spinal cord injury (SCI) model.
Tue Oct 12 00:00:00 UTC 2021
Bazedoxifene, a Selective Estrogen Receptor Modulator, Promotes Functional Recovery in a Spinal Cord Injury Rat Model.
International journal of molecular sciences
Kim Y,Roh EJ,Joshi HP,Shin HE,Choi H,Kwon SY,Sohn S,Han I
40-2300 was used in Immunocytochemistry to examine the effects of BZA in a rat spinal cord injury (SCI) model.
Tue Oct 12 00:00:00 UTC 2021
Asymmetric distribution of dynamin-2 and β-catenin relative to tight junction spikes in alveolar epithelial cells.
Tissue barriers
Lynn KS,Easley KF,Martinez FJ,Reed RC,Schlingmann B,Koval M
40-2300 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to suggest a novel role for dynamin-2 in tight junction spike formation by reorienting junction-associated actin.
Sat Jul 03 00:00:00 UTC 2021
Therapeutic B-cell depletion reverses progression of Alzheimer's disease.
Nature communications
Kim K,Wang X,Ragonnaud E,Bodogai M,Illouz T,DeLuca M,McDevitt RA,Gusev F,Okun E,Rogaev E,Biragyn A
40-2300 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to show that AD is associated with accumulation of activated B cells in circulation, and with infiltration of B cells into the brain parenchyma, resulting in immunoglobulin deposits around Aß plaques.
Mon Apr 12 00:00:00 UTC 2021
A role for early oral exposure to house dust mite allergens through breast milk in IgE-mediated food allergy susceptibility.
The Journal of allergy and clinical immunology
Rekima A,Bonnart C,Macchiaverni P,Metcalfe J,Tulic MK,Halloin N,Rekima S,Genuneit J,Zanelli S,Medeiros S,Palmer DJ,Prescott S,Verhasselt V
40-2300 was used in Immunocytochemistry to determine whether oral exposure to Dermatophagoides pteronyssinus through breast milk affects gut mucosal immunity with long-term effects on IgE-mediated food allergy susceptibility.
Fri May 01 00:00:00 UTC 2020
R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth.
Cell death and differentiation
De Cian MC,Gregoire EP,Le Rolle M,Lachambre S,Mondin M,Bell S,Guigon CJ,Chassot AA,Chaboissier MC
40-2300 was used in Immunohistochemistry (Paraffin) to find that RSPO2/Rspo2 expression is restricted to the oocyte of developing follicles in both human and mouse ovaries from the beginning of the follicular growth.
Thu Oct 01 00:00:00 UTC 2020
R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth.
Cell death and differentiation
De Cian MC,Gregoire EP,Le Rolle M,Lachambre S,Mondin M,Bell S,Guigon CJ,Chassot AA,Chaboissier MC
40-2300 was used in Immunohistochemistry (Paraffin) to find that RSPO2/Rspo2 expression is restricted to the oocyte of developing follicles in both human and mouse ovaries from the beginning of the follicular growth.
Thu Oct 01 00:00:00 UTC 2020
R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth.
Cell death and differentiation
De Cian MC,Gregoire EP,Le Rolle M,Lachambre S,Mondin M,Bell S,Guigon CJ,Chassot AA,Chaboissier MC
40-2300 was used in Immunohistochemistry (Paraffin) to find that RSPO2/Rspo2 expression is restricted to the oocyte of developing follicles in both human and mouse ovaries from the beginning of the follicular growth.
Thu Oct 01 00:00:00 UTC 2020
R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth.
Cell death and differentiation
De Cian MC,Gregoire EP,Le Rolle M,Lachambre S,Mondin M,Bell S,Guigon CJ,Chassot AA,Chaboissier MC
40-2300 was used in Immunohistochemistry (Paraffin) to find that RSPO2/Rspo2 expression is restricted to the oocyte of developing follicles in both human and mouse ovaries from the beginning of the follicular growth.
Thu Oct 01 00:00:00 UTC 2020
Cellulose Nanofibril Hydrogel Promotes Hepatic Differentiation of Human Liver Organoids.
Advanced healthcare materials
Krüger M,Oosterhoff LA,van Wolferen ME,Schiele SA,Walther A,Geijsen N,De Laporte L,van der Laan LJW,Kock LM,Spee B
40-2300 was used in Immunohistochemistry to investigate the potential of cellulose nanofibril (CNF) hydrogel to serve as an alternative clinical grade scaffold to differentiate liver organoids.
Sun Mar 01 00:00:00 UTC 2020
Elevated TRPV4 Levels Contribute to Endothelial Damage and Scarring in Experimental Spinal Cord Injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Kumar H,Lim CS,Choi H,Joshi HP,Kim KT,Kim YH,Park CK,Kim HM,Han IB
40-2300 was used in Immunohistochemistry to report the expression and contribution of TRPV4 in the pathology of scarring and endothelial and secondary damage after SCI.
Wed Feb 26 00:00:00 UTC 2020
Elevated TRPV4 Levels Contribute to Endothelial Damage and Scarring in Experimental Spinal Cord Injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Kumar H,Lim CS,Choi H,Joshi HP,Kim KT,Kim YH,Park CK,Kim HM,Han IB
40-2300 was used in Immunohistochemistry to report the expression and contribution of TRPV4 in the pathology of scarring and endothelial and secondary damage after SCI.
Wed Feb 26 00:00:00 UTC 2020
Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging.
Frontiers in bioengineering and biotechnology
Salman MM,Marsh G,Kusters I,Delincé M,Di Caprio G,Upadhyayula S,de Nola G,Hunt R,Ohashi KG,Gray T,Shimizu F,Sano Y,Kanda T,Obermeier B,Kirchhausen T
40-2300 was used in Immunocytochemistry-immunoflourescence to validate barrier function of our brain microvessel-on-a-chip by measuring permeability of fluorescent dextran and a human monoclonal antibody.
Fri Aug 02 00:00:00 UTC 2024
Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging.
Frontiers in bioengineering and biotechnology
Salman MM,Marsh G,Kusters I,Delincé M,Di Caprio G,Upadhyayula S,de Nola G,Hunt R,Ohashi KG,Gray T,Shimizu F,Sano Y,Kanda T,Obermeier B,Kirchhausen T
40-2300 was used in Immunocytochemistry-immunoflourescence to validate barrier function of our brain microvessel-on-a-chip by measuring permeability of fluorescent dextran and a human monoclonal antibody.
Fri Aug 02 00:00:00 UTC 2024
Increased Catecholamine Levels and Inflammatory Mediators Alter Barrier Properties of Brain Microvascular Endothelial Cells in vitro.
Frontiers in cardiovascular medicine
Ittner C,Burek M,Störk S,Nagai M,Förster CY
40-2300 was used in Immunocytochemistry-immunoflourescence to demonstrate that the proteins forming the blood brain barrier (BBB) and the cell count are clearly influenced by catecholamine (CAT) and INF applied under oxygen glucose deprivation (OGD) conditions.
Mon Sep 28 00:00:00 UTC 2020
Increased Catecholamine Levels and Inflammatory Mediators Alter Barrier Properties of Brain Microvascular Endothelial Cells in vitro.
Frontiers in cardiovascular medicine
Ittner C,Burek M,Störk S,Nagai M,Förster CY
40-2300 was used in Immunocytochemistry-immunoflourescence to demonstrate that the proteins forming the blood brain barrier (BBB) and the cell count are clearly influenced by catecholamine (CAT) and INF applied under oxygen glucose deprivation (OGD) conditions.
Mon Sep 28 00:00:00 UTC 2020
Increased Catecholamine Levels and Inflammatory Mediators Alter Barrier Properties of Brain Microvascular Endothelial Cells in vitro.
Frontiers in cardiovascular medicine
Ittner C,Burek M,Störk S,Nagai M,Förster CY
40-2300 was used in Immunocytochemistry-immunoflourescence to demonstrate that the proteins forming the blood brain barrier (BBB) and the cell count are clearly influenced by catecholamine (CAT) and INF applied under oxygen glucose deprivation (OGD) conditions.
Mon Sep 28 00:00:00 UTC 2020
Two-Stage Interpretation of Changes in TEER of Intestinal Epithelial Layers Protected by Adhering Bifidobacteria During E. coli Challenges.
Frontiers in microbiology
Yuan L,van der Mei HC,Busscher HJ,Peterson BW
40-2300 was used in Immunocytochemistry-immunoflourescence to interpret single-time TEER in two.
Sat Mar 30 00:00:00 UTC 2024
Two-Stage Interpretation of Changes in TEER of Intestinal Epithelial Layers Protected by Adhering Bifidobacteria During E. coli Challenges.
Frontiers in microbiology
Yuan L,van der Mei HC,Busscher HJ,Peterson BW
40-2300 was used in Immunocytochemistry-immunoflourescence to interpret single-time TEER in two.
Sat Mar 30 00:00:00 UTC 2024
Neurotrophic Factors Protect the Intestinal Barrier from Rotavirus Insult in Mice.
mBio
Hagbom M,De Faria FM,Winberg ME,Westerberg S,Nordgren J,Sharma S,Keita ÅV,Loitto V,Magnusson KE,Svensson L
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Tue Jan 21 00:00:00 UTC 2020
Antrodia cinnamomea Confers Obesity Resistance and Restores Intestinal Barrier Integrity in Leptin-deficient Obese Mice.
Nutrients
Tsai YT,Ruan JW,Chang CS,Ko ML,Chou HC,Lin CC,Lin CM,Huang CT,Wei YS,Liao EC,Chen HY,Kao CY,Chan HL
40-2300 was used in Immunocytochemistry to study the effect of antrodia cinnamomea on obesity in mice.
Tue Mar 10 00:00:00 UTC 2020
Antrodia cinnamomea Confers Obesity Resistance and Restores Intestinal Barrier Integrity in Leptin-deficient Obese Mice.
Nutrients
Tsai YT,Ruan JW,Chang CS,Ko ML,Chou HC,Lin CC,Lin CM,Huang CT,Wei YS,Liao EC,Chen HY,Kao CY,Chan HL
40-2300 was used in Immunocytochemistry to study the effect of antrodia cinnamomea on obesity in mice.
Tue Mar 10 00:00:00 UTC 2020
Antrodia cinnamomea Confers Obesity Resistance and Restores Intestinal Barrier Integrity in Leptin-deficient Obese Mice.
Nutrients
Tsai YT,Ruan JW,Chang CS,Ko ML,Chou HC,Lin CC,Lin CM,Huang CT,Wei YS,Liao EC,Chen HY,Kao CY,Chan HL
40-2300 was used in Immunocytochemistry to study the effect of antrodia cinnamomea on obesity in mice.
Tue Mar 10 00:00:00 UTC 2020
Impact of viral disease hypophagia on pig jejunal function and integrity.
PloS one
Helm ET,Curry SM,De Mille CM,Schweer WP,Burrough ER,Gabler NK
40-2300 was used in Immunohistochemistry to determine the impact of Porcine Reproductive and Respiratory Syndrome virus (PRRSV) and feed intake on parameters of jejunal function and integrity in growing pigs.
Fri Apr 10 00:00:00 UTC 2020
Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells.
Cell reports
Takeishi K,Collin de l'Hortet A,Wang Y,Handa K,Guzman-Lepe J,Matsubara K,Morita K,Jang S,Haep N,Florentino RM,Yuan F,Fukumitsu K,Tobita K,Sun W,Franks J,Delgado ER,Shapiro EM,Fraunhoffer NA,Duncan AW,Yagi H,Mashimo T,Fox IJ,Soto-Gutierrez A
40-2300 was used in Immunohistochemistry to developed protocols for hepatocyte-, cholangiocyte-, and endothelial-cell differentiation of human induced pluripotent stem cells (iPSCs).
Tue Jun 02 00:00:00 UTC 2020
Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells.
Cell reports
Takeishi K,Collin de l'Hortet A,Wang Y,Handa K,Guzman-Lepe J,Matsubara K,Morita K,Jang S,Haep N,Florentino RM,Yuan F,Fukumitsu K,Tobita K,Sun W,Franks J,Delgado ER,Shapiro EM,Fraunhoffer NA,Duncan AW,Yagi H,Mashimo T,Fox IJ,Soto-Gutierrez A
40-2300 was used in Immunohistochemistry to developed protocols for hepatocyte-, cholangiocyte-, and endothelial-cell differentiation of human induced pluripotent stem cells (iPSCs).
Tue Jun 02 00:00:00 UTC 2020
ROCK2 inhibition triggers the collective invasion of colorectal adenocarcinomas.
The EMBO journal
Libanje F,Raingeaud J,Luan R,Thomas Z,Zajac O,Veiga J,Marisa L,Adam J,Boige V,Malka D,Goéré D,Hall A,Soazec JY,Prall F,Gelli M,Dartigues P,Jaulin F
40-2300 was used in Immunohistochemistry-immunofluorescence to identify FARP2 as the Rac1 GEF necessary for CRC collective invasion.
Mon Jul 15 00:00:00 UTC 2019
EspF is crucial for Citrobacter rodentium-induced tight junction disruption and lethality in immunocompromised animals.
PLoS pathogens
Xia X,Liu Y,Hodgson A,Xu D,Guo W,Yu H,She W,Zhou C,Lan L,Fu K,Vallance BA,Wan F
40-2300 was used in Western Blotting to identify a critical pathophysiological function for EspF during Citrobacter rodentium infection in immunocompromised animals.
Sat Jun 01 00:00:00 UTC 2019
Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650.
Pharmaceutics
Ladel S,Schlossbauer P,Flamm J,Luksch H,Mizaikoff B,Schindowski K
40-2300 was used in Immunocytochemistry to present a novel and comprehensive characterisation of porcine olfactory (OEPC) and respiratory (REPC) primary cells against the nasal tumour cell line RPMI 2650.
Thu Aug 01 00:00:00 UTC 2019
Inhibitory Effects of Sodium Alginate on Hepatic Steatosis in Mice Induced by a Methionine- and Choline-deficient Diet.
Marine drugs
Kawauchi S,Horibe S,Sasaki N,Tanahashi T,Mizuno S,Hamaguchi T,Rikitake Y
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Sat Feb 09 00:00:00 UTC 2019
Inhibitory Effects of Sodium Alginate on Hepatic Steatosis in Mice Induced by a Methionine- and Choline-deficient Diet.
Marine drugs
Kawauchi S,Horibe S,Sasaki N,Tanahashi T,Mizuno S,Hamaguchi T,Rikitake Y
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Sat Feb 09 00:00:00 UTC 2019
Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration.
eLife
Carvalho JR,Fortunato IC,Fonseca CG,Pezzarossa A,Barbacena P,Dominguez-Cejudo MA,Vasconcelos FF,Santos NC,Carvalho FA,Franco CA
40-2300 was used in Immunohistochemistry to highlight how non-canonical Wnt signalling coordinates collective cell behaviour during vascular morphogenesis by fine-tuning junctional mechanocoupling between endothelial cells.
Thu Jun 27 00:00:00 UTC 2019
Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration.
eLife
Carvalho JR,Fortunato IC,Fonseca CG,Pezzarossa A,Barbacena P,Dominguez-Cejudo MA,Vasconcelos FF,Santos NC,Carvalho FA,Franco CA
40-2300 was used in Immunohistochemistry to highlight how non-canonical Wnt signalling coordinates collective cell behaviour during vascular morphogenesis by fine-tuning junctional mechanocoupling between endothelial cells.
Thu Jun 27 00:00:00 UTC 2019
Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration.
eLife
Carvalho JR,Fortunato IC,Fonseca CG,Pezzarossa A,Barbacena P,Dominguez-Cejudo MA,Vasconcelos FF,Santos NC,Carvalho FA,Franco CA
40-2300 was used in Immunohistochemistry to highlight how non-canonical Wnt signalling coordinates collective cell behaviour during vascular morphogenesis by fine-tuning junctional mechanocoupling between endothelial cells.
Thu Jun 27 00:00:00 UTC 2019
Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration.
eLife
Carvalho JR,Fortunato IC,Fonseca CG,Pezzarossa A,Barbacena P,Dominguez-Cejudo MA,Vasconcelos FF,Santos NC,Carvalho FA,Franco CA
40-2300 was used in Immunohistochemistry to highlight how non-canonical Wnt signalling coordinates collective cell behaviour during vascular morphogenesis by fine-tuning junctional mechanocoupling between endothelial cells.
Thu Jun 27 00:00:00 UTC 2019
Organoid single cell profiling identifies a transcriptional signature of glomerular disease.
JCI insight
Harder JL,Menon R,Otto EA,Zhou J,Eddy S,Wys NL,O'Connor C,Luo J,Nair V,Cebrian C,Spence JR,Bitzer M,Troyanskaya OG,Hodgin JB,Wiggins RC,Freedman BS,Kretzler M
40-2300 was used in Immunocytochemistry to demonstrate an approach to identifying potentially novel molecular programs involved in the pathogenesis of glomerulopathies.
Thu Jan 10 00:00:00 UTC 2019
Retinal Phenotype in the rd9 Mutant Mouse, a Model of X-Linked RP.
Frontiers in neuroscience
Falasconi A,Biagioni M,Novelli E,Piano I,Gargini C,Strettoi E
40-2300 was used in Immunohistochemistry-immunofluorescence to find that in rd9 retinas rod (but not cone) death is the main cause of decrease in ONL thickness and that degeneration shows a high degree of intraretinal variation.
Wed Sep 30 00:00:00 UTC 2020
Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms.
American journal of human genetics
Forbes TA,Howden SE,Lawlor K,Phipson B,Maksimovic J,Hale L,Wilson S,Quinlan C,Ho G,Holman K,Bennetts B,Crawford J,Trnka P,Oshlack A,Patel C,Mallett A,Simons C,Little MH
40-2300 was used in Immunocytochemistry-immunoflourescence to study the cellular mechanisms responsible for renal disease presentation following IFT140 mutation.
Thu May 03 00:00:00 UTC 2018
Wdpcp promotes epicardial EMT and epicardium-derived cell migration to facilitate coronary artery remodeling.
Science signaling
Liu X,Wang Y,Liu F,Zhang M,Song H,Zhou B,Lo CW,Tong S,Hu Z,Zhang Z
40-2300 was used in Immunohistochemistry-immunofluorescence to show that the Wdpcp mutant mice will be a useful tool to dissect the molecular mechanisms that govern the remodeling of the primitive plexus during coronary development.
Tue Feb 27 00:00:00 UTC 2018
Characterization of human fetal brain endothelial cells reveals barrier properties suitable for in vitro modeling of the BBB with syngenic co-cultures.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Andrews AM,Lutton EM,Cannella LA,Reichenbach N,Razmpour R,Seasock MJ,Kaspin SJ,Merkel SF,Langford D,Persidsky Y,Ramirez SH
40-2300 was used in Immunohistochemistry-immunofluorescence to provide a means to overcome previous challenges that limited successful barrier formation by fBMVECs.
Tue May 01 00:00:00 UTC 2018
Characterization of human fetal brain endothelial cells reveals barrier properties suitable for in vitro modeling of the BBB with syngenic co-cultures.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Andrews AM,Lutton EM,Cannella LA,Reichenbach N,Razmpour R,Seasock MJ,Kaspin SJ,Merkel SF,Langford D,Persidsky Y,Ramirez SH
40-2300 was used in Immunohistochemistry-immunofluorescence to provide a means to overcome previous challenges that limited successful barrier formation by fBMVECs.
Tue May 01 00:00:00 UTC 2018
Galectin-3 modulates the polarized surface delivery of β1-integrin in epithelial cells.
Journal of cell science
Hönig E,Ringer K,Dewes J,von Mach T,Kamm N,Kreitzer G,Jacob R
40-2300 was used in Immunocytochemistry-immunoflourescence to suggest that galectin-3 modulates the surface distribution of Β1-integrin and affects the morphogenesis of polarized cells.
Mon Jun 11 00:00:00 UTC 2018
Cadherin-6B proteolytic N-terminal fragments promote chick cranial neural crest cell delamination by regulating extracellular matrix degradation.
Developmental biology
Schiffmacher AT,Adomako-Ankomah A,Xie V,Taneyhill LA
40-2300 was used in Immunohistochemistry to highlight a new function for Cad6B NTFs and provide insight into how cadherins regulate cellular delamination during normal developmental EMTs as well as aberrant EMTs that underlie human disease.
Sat Dec 01 00:00:00 UTC 2018
Cadherin-6B proteolytic N-terminal fragments promote chick cranial neural crest cell delamination by regulating extracellular matrix degradation.
Developmental biology
Schiffmacher AT,Adomako-Ankomah A,Xie V,Taneyhill LA
40-2300 was used in Immunohistochemistry to highlight a new function for Cad6B NTFs and provide insight into how cadherins regulate cellular delamination during normal developmental EMTs as well as aberrant EMTs that underlie human disease.
Sat Dec 01 00:00:00 UTC 2018
Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues.
Nature communications
Lai HM,Liu AKL,Ng HHM,Goldfinger MH,Chau TW,DeFelice J,Tilley BS,Wong WM,Wu W,Gentleman SM
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Wed Mar 14 00:00:00 UTC 2018
Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues.
Nature communications
Lai HM,Liu AKL,Ng HHM,Goldfinger MH,Chau TW,DeFelice J,Tilley BS,Wong WM,Wu W,Gentleman SM
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Wed Mar 14 00:00:00 UTC 2018
Stabilization of HIF-2α impacts pancreas growth.
Scientific reports
Flores-Martínez A,García-Núñez A,Rojas A,Cano DA
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunohistochemistry
Wed Sep 12 00:00:00 UTC 2018
Helicobacter pylori Infection Modulates Host Cell Metabolism through VacA-Dependent Inhibition of mTORC1.
Cell host & microbe
Kim IJ,Lee J,Oh SJ,Yoon MS,Jang SS,Holland RL,Reno ML,Hamad MN,Maeda T,Chung HJ,Chen J,Blanke SR
40-2300 was used in Immunocytochemistry to support a model that Hp modulate host cell metabolism through the action of VacA at mitochondria.
Wed May 09 00:00:00 UTC 2018
Targeting Glioma Stem Cell-Derived Pericytes Disrupts the Blood-Tumor Barrier and Improves Chemotherapeutic Efficacy.
Cell stem cell
Zhou W,Chen C,Shi Y,Wu Q,Gimple RC,Fang X,Huang Z,Zhai K,Ke SQ,Ping YF,Feng H,Rich JN,Yu JS,Bao S,Bian XW
40-2300 was used in Immunohistochemistry-immunofluorescence to highlight the clinical potential of targeting neoplastic pericytes to significantly improve treatment of brain tumors.
Thu Nov 02 00:00:00 UTC 2017
Targeting Glioma Stem Cell-Derived Pericytes Disrupts the Blood-Tumor Barrier and Improves Chemotherapeutic Efficacy.
Cell stem cell
Zhou W,Chen C,Shi Y,Wu Q,Gimple RC,Fang X,Huang Z,Zhai K,Ke SQ,Ping YF,Feng H,Rich JN,Yu JS,Bao S,Bian XW
40-2300 was used in Immunohistochemistry-immunofluorescence to highlight the clinical potential of targeting neoplastic pericytes to significantly improve treatment of brain tumors.
Thu Nov 02 00:00:00 UTC 2017
Systemic Injection of RPE65-Programmed Bone Marrow-Derived Cells Prevents Progression of Chronic Retinal Degeneration.
Molecular therapy : the journal of the American Society of Gene Therapy
Qi X,Pay SL,Yan Y,Thomas J,Lewin AS,Chang LJ,Grant MB,Boulton ME
402300 was used in immunohistochemistry - paraffin section to evaluate the efficacy of systemically administered RPE65-programmed bone marrow-derived cells to prevent visual loss in a mouse model of age-related macular degeneration
Wed Apr 05 00:00:00 UTC 2017
In Vitro Study of Receptor-Mediated Silica Nanoparticles Delivery across Blood-Brain Barrier.
ACS applied materials & interfaces
Song Y,Du D,Li L,Xu J,Dutta P,Lin Y
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunocytochemistry
Wed Jun 21 00:00:00 UTC 2017
Massively Increased Caries Susceptibility in an Irf6 Cleft Lip/Palate Model.
Journal of dental research
Tamasas B,Cox TC
402300 was used in immunohistochemistry - paraffin section to characterize conditional knockout mice in which Irf6 is ablated only in the late embryonic oral epithelium
Wed Mar 01 00:00:00 UTC 2017
Complement C5aR1 Signaling Promotes Polarization and Proliferation of Embryonic Neural Progenitor Cells through PKCζ.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Coulthard LG,Hawksworth OA,Li R,Balachandran A,Lee JD,Sepehrband F,Kurniawan N,Jeanes A,Simmons DG,Wolvetang E,Woodruff TM
40-2300 was used in Immunocytochemistry-immunoflourescence to aid in identifying a functional role for C5a-C5aR1 receptor signalling in mammalian neurogenesis.
Wed May 31 00:00:00 UTC 2017
Multifaceted Mechanisms of WY-14643 to Stabilize the Blood-Brain Barrier in a Model of Traumatic Brain Injury.
Frontiers in molecular neuroscience
Neuhaus W,Krämer T,Neuhoff A,Gölz C,Thal SC,Förster CY
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Western Blot
Thu Oct 01 00:00:00 UTC 2020
E-cadherin cleavage by MT2-MMP regulates apical junctional signaling and epithelial homeostasis in the intestine.
Journal of cell science
Gómez-Escudero J,Moreno V,Martín-Alonso M,Hernández-Riquer MV,Feinberg T,Colmenar Á,Calvo E,Camafeita E,Martínez F,Oudhoff MJ,Weiss SJ,Arroyo AG
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunocytochemistry
Fri Dec 01 00:00:00 UTC 2017
E-cadherin cleavage by MT2-MMP regulates apical junctional signaling and epithelial homeostasis in the intestine.
Journal of cell science
Gómez-Escudero J,Moreno V,Martín-Alonso M,Hernández-Riquer MV,Feinberg T,Colmenar Á,Calvo E,Camafeita E,Martínez F,Oudhoff MJ,Weiss SJ,Arroyo AG
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunocytochemistry
Fri Dec 01 00:00:00 UTC 2017
Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity.
Nature communications
Salomon J,Gaston C,Magescas J,Duvauchelle B,Canioni D,Sengmanivong L,Mayeux A,Michaux G,Campeotto F,Lemale J,Viala J,Poirier F,Minc N,Schmitz J,Brousse N,Ladoux B,Goulet O,Delacour D
402300 was used in immunocytochemistry and immunohistochemistry - paraffin section to show that the absence of EpCAM in enterocytes results in an aberrant apical domain
Fri Jan 13 00:00:00 UTC 2017
Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity.
Nature communications
Salomon J,Gaston C,Magescas J,Duvauchelle B,Canioni D,Sengmanivong L,Mayeux A,Michaux G,Campeotto F,Lemale J,Viala J,Poirier F,Minc N,Schmitz J,Brousse N,Ladoux B,Goulet O,Delacour D
402300 was used in immunocytochemistry and immunohistochemistry - paraffin section to show that the absence of EpCAM in enterocytes results in an aberrant apical domain
Fri Jan 13 00:00:00 UTC 2017
Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis.
The Journal of clinical investigation
Egan CE,Sodhi CP,Good M,Lin J,Jia H,Yamaguchi Y,Lu P,Ma C,Branca MF,Weyandt S,Fulton WB,Niño DF,Prindle T,Ozolek JA,Hackam DJ
40-2300 was used in western blot to determine the role of the toll-like receptor 4-mediated lymphocyte influx as an inducer of neonatal necrotizing enterocolitis
Mon Feb 01 00:00:00 UTC 2016
Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis.
The Journal of clinical investigation
Egan CE,Sodhi CP,Good M,Lin J,Jia H,Yamaguchi Y,Lu P,Ma C,Branca MF,Weyandt S,Fulton WB,Niño DF,Prindle T,Ozolek JA,Hackam DJ
40-2300 was used in western blot to determine the role of the toll-like receptor 4-mediated lymphocyte influx as an inducer of neonatal necrotizing enterocolitis
Mon Feb 01 00:00:00 UTC 2016
Isolation, culture and characterization of primary mouse RPE cells.
Nature protocols
Fernandez-Godino R,Garland DL,Pierce EA
40-2300 was used in immunocytochemistry to characterize primary mouse RPE cells by culture and isolation
Fri Jul 01 00:00:00 UTC 2016
Enhanced Re-Endothelialization of Decellularized Rat Lungs.
Tissue engineering. Part C, Methods
Stabler CT,Caires LC,Mondrinos MJ,Marcinkiewicz C,Lazarovici P,Wolfson MR,Lelkes PI
40-2300 was used in immunocytochemistry to assess the link between decellularized rat lungs and enhaced re-endothelialization
Sun May 01 00:00:00 UTC 2016
Murine junctional adhesion molecules JAM-B and JAM-C mediate endothelial and stellate cell interactions during hepatic fibrosis.
Cell adhesion & migration
Hintermann E,Bayer M,Ehser J,Aurrand-Lions M,Pfeilschifter JM,Imhof BA,Christen U
40-2300 was used in immunohistochemistry - frozen section to analyze mediation of stellate and endothelial cell interactions during hepatic fibrosis due to murine junctional adhesion molecules JAM-B and JAM-C
Sun Jul 03 00:00:00 UTC 2016
Murine junctional adhesion molecules JAM-B and JAM-C mediate endothelial and stellate cell interactions during hepatic fibrosis.
Cell adhesion & migration
Hintermann E,Bayer M,Ehser J,Aurrand-Lions M,Pfeilschifter JM,Imhof BA,Christen U
40-2300 was used in immunohistochemistry - frozen section to analyze mediation of stellate and endothelial cell interactions during hepatic fibrosis due to murine junctional adhesion molecules JAM-B and JAM-C
Sun Jul 03 00:00:00 UTC 2016
Silencing microRNA-143 protects the integrity of the blood-brain barrier: implications for methamphetamine abuse.
Scientific reports
Bai Y,Zhang Y,Hua J,Yang X,Zhang X,Duan M,Zhu X,Huang W,Chao J,Zhou R,Hu G,Yao H
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Western Blot
Fri Oct 21 00:00:00 UTC 2016
MICAL2 is a novel human cancer gene controlling mesenchymal to epithelial transition involved in cancer growth and invasion.
Oncotarget
Mariotti S,Barravecchia I,Vindigni C,Pucci A,Balsamo M,Libro R,Senchenko V,Dmitriev A,Jacchetti E,Cecchini M,Roviello F,Lai M,Broccoli V,Andreazzoli M,Mazzanti CM,Angeloni D
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Tue Jan 12 00:00:00 UTC 2016
Intrinsic FGF2 and FGF5 promotes angiogenesis of human aortic endothelial cells in 3D microfluidic angiogenesis system.
Scientific reports
Seo HR,Jeong HE,Joo HJ,Choi SC,Park CY,Kim JH,Choi JH,Cui LH,Hong SJ,Chung S,Lim DS
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Thu Jun 30 00:00:00 UTC 2016
Intrinsic FGF2 and FGF5 promotes angiogenesis of human aortic endothelial cells in 3D microfluidic angiogenesis system.
Scientific reports
Seo HR,Jeong HE,Joo HJ,Choi SC,Park CY,Kim JH,Choi JH,Cui LH,Hong SJ,Chung S,Lim DS
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Thu Jun 30 00:00:00 UTC 2016
Lung Microtissue Array to Screen the Fibrogenic Potential of Carbon Nanotubes.
Scientific reports
Chen Z,Wang Q,Asmani M,Li Y,Liu C,Li C,Lippmann JM,Wu Y,Zhao R
40-2300 was used in immunocytochemistry use a microtissue array system to examine the effects of multi-wall carbon nanotube exposure
Thu Aug 11 00:00:00 UTC 2016
Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea.
Journal of visualized experiments : JoVE
May-Simera H
40-2300 was used in immunohistochemistry to elucidate the planar-cell-polarity phenotypes in ciliopathy mouse mutant cochlea
Sun Feb 21 00:00:00 UTC 2016
Immunohistochemical expression of VDR is associated with reduced integrity of tight junction complex in psoriatic skin.
Journal of the European Academy of Dermatology and Venereology : JEADV
Visconti B,Paolino G,Carotti S,Pendolino AL,Morini S,Richetta AG,Calvieri S
40-2300 was used in immunohistochemistry (paraffin) to study the role of vitamin D/VDR signaling in tissue barrier function related to psoriasis.
Thu Oct 01 00:00:00 UTC 2015
Immunohistochemical expression of VDR is associated with reduced integrity of tight junction complex in psoriatic skin.
Journal of the European Academy of Dermatology and Venereology : JEADV
Visconti B,Paolino G,Carotti S,Pendolino AL,Morini S,Richetta AG,Calvieri S
40-2300 was used in immunohistochemistry (paraffin) to study the role of vitamin D/VDR signaling in tissue barrier function related to psoriasis.
Thu Oct 01 00:00:00 UTC 2015
Upregulation of Shiga toxin receptor CD77/Gb3 and interleukin-1β expression in the brain of EHEC patients with hemolytic uremic syndrome and neurologic symptoms.
Brain pathology (Zurich, Switzerland)
Hagel C,Krasemann S,Löffler J,Püschel K,Magnus T,Glatzel M
40-2300 was used in immunohistochemistry to describe the post-mortem neuropathological characteristics of five EHEC patients.
Sun Mar 01 00:00:00 UTC 2015
Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification.
Development (Cambridge, England)
O'Shaughnessy-Kirwan A,Signolet J,Costello I,Gharbi S,Hendrich B
40-2300 was used in immunocytochemistry to assess lineage specification constrained by gene expression of the chromatin remodeling protein CHD4
Sat Aug 01 00:00:00 UTC 2015
Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification.
Development (Cambridge, England)
O'Shaughnessy-Kirwan A,Signolet J,Costello I,Gharbi S,Hendrich B
40-2300 was used in immunocytochemistry to assess lineage specification constrained by gene expression of the chromatin remodeling protein CHD4
Sat Aug 01 00:00:00 UTC 2015
Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification.
Development (Cambridge, England)
O'Shaughnessy-Kirwan A,Signolet J,Costello I,Gharbi S,Hendrich B
40-2300 was used in immunocytochemistry to assess lineage specification constrained by gene expression of the chromatin remodeling protein CHD4
Sat Aug 01 00:00:00 UTC 2015
Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis.
Journal of molecular medicine (Berlin, Germany)
Peng H,Li C,Kadow S,Henry BD,Steinmann J,Becker KA,Riehle A,Beckmann N,Wilker B,Li PL,Pritts T,Edwards MJ,Zhang Y,Gulbins E,Grassmé H
40-2300 was used in immunocytochemistry and immunohistochemistry (paraffin) to examine the role of the mammalian acid sphingomyelinase/ceramide system in the development of lung edema caused by S. aureus.
Mon Jun 01 00:00:00 UTC 2015
The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment.
American journal of physiology. Gastrointestinal and liver physiology
de Vallière C,Vidal S,Clay I,Jurisic G,Tcymbarevich I,Lang S,Ludwig MG,Okoniewski M,Eloranta JJ,Kullak-Ublick GA,Wagner CA,Rogler G,Seuwen K
40-2300 was used in immunocytochemistry to study OGR1-mediated, pH-dependent signaling pathways in intestinal epithelial cells.
Tue Sep 15 00:00:00 UTC 2015
A Novel Dynamic Neonatal Blood-Brain Barrier on a Chip.
PloS one
Deosarkar SP,Prabhakarpandian B,Wang B,Sheffield JB,Krynska B,Kiani MF
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Mon Jun 13 00:00:00 UTC 2016
A Novel Dynamic Neonatal Blood-Brain Barrier on a Chip.
PloS one
Deosarkar SP,Prabhakarpandian B,Wang B,Sheffield JB,Krynska B,Kiani MF
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Mon Jun 13 00:00:00 UTC 2016
Liver Sinusoidal Endothelial Cells Escape Senescence by Loss of p19ARF.
PloS one
Koudelkova P,Weber G,Mikulits W
40-2300 was used in immunocytochemistry to characterize the role of p19ARF depletion and cell escape in regards to liver sinusoidal endothelial cells
Wed Jun 08 00:00:00 UTC 2016
Bovine posterior limbus: an evaluation of an alternative source for corneal endothelial and trabecular meshwork stem/progenitor cells.
Stem cells and development
Yu WY,Grierson I,Sheridan C,Lo AC,Wong DS
40-2300 was used in Immunocytochemistry to show that PET cells are present in the posterior limbus of bovine eyes and that they can be successfully cultured and expanded.
Sun Mar 01 00:00:00 UTC 2015
Twist1-induced dissemination preserves epithelial identity and requires E-cadherin.
The Journal of cell biology
Shamir ER,Pappalardo E,Jorgens DM,Coutinho K,Tsai WT,Aziz K,Auer M,Tran PT,Bader JS,Ewald AJ
40-2300 was used in immunohistochemistry - frozen section to characterize the role of Twist1-induced dissemination that requires E-cadherin and preserves epithelial identity
Mon Mar 03 00:00:00 UTC 2014
Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes.
Journal of cell science
Zemljic-Harpf AE,Godoy JC,Platoshyn O,Asfaw EK,Busija AR,Domenighetti AA,Ross RS
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Sat Mar 01 00:00:00 UTC 2014
Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes.
Journal of cell science
Zemljic-Harpf AE,Godoy JC,Platoshyn O,Asfaw EK,Busija AR,Domenighetti AA,Ross RS
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Sat Mar 01 00:00:00 UTC 2014
Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes.
Journal of cell science
Zemljic-Harpf AE,Godoy JC,Platoshyn O,Asfaw EK,Busija AR,Domenighetti AA,Ross RS
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Sat Mar 01 00:00:00 UTC 2014
Retinal pigment epithelial cell death by the alternative complement cascade: role of membrane regulatory proteins, calcium, PKC, and oxidative stress.
Investigative ophthalmology & visual science
Yang P,Baciu P,Kerrigan BC,Etheridge M,Sung E,Toimil BA,Berchuck JE,Jaffe GJ
40-2300 was used in immunocytochemistry to use a new model which initiates alternate pathway activation on retinal pigment epithelial cells to investigate cell death.
Tue May 06 00:00:00 UTC 2014
Intestinal and systemic inflammatory responses are positively associated with sulfidogenic bacteria abundance in high-fat-fed male C57BL/6J mice.
The Journal of nutrition
Shen W,Wolf PG,Carbonero F,Zhong W,Reid T,Gaskins HR,McIntosh MK
40-2300 was used in western blot to test if a high fat rich in saturated fat stimulates sulfidogenic bacteria and study the intestinal and systemic inflammatory responses.
Fri Aug 01 00:00:00 UTC 2014
Impaired intestinal mucosal barrier upon ischemia-reperfusion: "patching holes in the shield with a simple surgical method".
BioMed research international
Rosero O,Ónody P,Kovács T,Molnár D,Lotz G,Tóth S,Turóczi Z,Fülöp A,Garbaisz D,Harsányi L,Szijártó A
40-2300 was used in immunohistochemistry - paraffin section to study the effect of ischemia-reperfusion on intestinal mucosal barrier
Thu Feb 12 00:00:00 UTC 2015
Impaired intestinal mucosal barrier upon ischemia-reperfusion: "patching holes in the shield with a simple surgical method".
BioMed research international
Rosero O,Ónody P,Kovács T,Molnár D,Lotz G,Tóth S,Turóczi Z,Fülöp A,Garbaisz D,Harsányi L,Szijártó A
40-2300 was used in immunohistochemistry - paraffin section to study the effect of ischemia-reperfusion on intestinal mucosal barrier
Thu Feb 12 00:00:00 UTC 2015
An in vitro blood-brain barrier model combining shear stress and endothelial cell/astrocyte co-culture.
Journal of neuroscience methods
Takeshita Y,Obermeier B,Cotleur A,Sano Y,Kanda T,Ransohoff RM
40-2300 was used in immunocytochemistry to evaluate an in vitro blood-brain barrier model.
Wed Jul 30 00:00:00 UTC 2014
Disruption of astrocyte-vascular coupling and the blood-brain barrier by invading glioma cells.
Nature communications
Watkins S,Robel S,Kimbrough IF,Robert SM,Ellis-Davies G,Sontheimer H
40-2300 was used in immunohistochemistry - free floating to characterize invading glioma cells and their disruption of astrocyte-vascular coupling and the blood-brain barrier
Thu Jun 19 00:00:00 UTC 2014
Analysis of angiogenesis in the developing mouse central nervous system.
Methods in molecular biology (Clifton, N.J.)
Ziegler N,Plate KH,Liebner S
40-2300 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to describe how to fix, dissect, stain, and analyze the developing hindbrain vasculature.
Mon Sep 29 00:00:00 UTC 2014
Phosphorylation decreases ubiquitylation of the thiazide-sensitive cotransporter NCC and subsequent clathrin-mediated endocytosis.
The Journal of biological chemistry
Rosenbaek LL,Kortenoeven ML,Aroankins TS,Fenton RA
Fri May 09 00:00:00 UTC 2014
Luminal mitosis drives epithelial cell dispersal within the branching ureteric bud.
Developmental cell
Packard A,Georgas K,Michos O,Riccio P,Cebrian C,Combes AN,Ju A,Ferrer-Vaquer A,Hadjantonakis AK,Zong H,Little MH,Costantini F
40-2300 was used in immunohistochemistry to observe ureteric bud cell behaviors in developing mouse kidneys.
Mon Nov 11 00:00:00 UTC 2013
Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures.
The Journal of cell biology
Cerruti B,Puliafito A,Shewan AM,Yu W,Combes AN,Little MH,Chianale F,Primo L,Serini G,Mostov KE,Celani A,Gamba A
40-2300 was used in immunocytochemistry to characterize the growth of epithelial structures regulated by polarity, out-of-equilibrium dynamics, and cell division.
Mon Oct 28 00:00:00 UTC 2013
Echovirus 1 entry into polarized Caco-2 cells depends on dynamin, cholesterol, and cellular factors associated with macropinocytosis.
Journal of virology
Krieger SE,Kim C,Zhang L,Marjomaki V,Bergelson JM
40-2300 was used in immunocytochemistry to investigate the contribution of macropinocytosis to echovirus cell entry.
Thu Aug 01 00:00:00 UTC 2013
Heme modulates intestinal epithelial cell activation: involvement of NADPHox-derived ROS signaling.
American journal of physiology. Cell physiology
Barcellos-de-Souza P,Moraes JA,de-Freitas-Junior JC,Morgado-Díaz JA,Barja-Fidalgo C,Arruda MA
40-2300 was used in immunocytochemistry to study the effects of heme upon a nontransformed small intestine epithelial cell line.
Tue Jan 15 00:00:00 UTC 2013
MUC4 overexpression augments cell migration and metastasis through EGFR family proteins in triple negative breast cancer cells.
PloS one
Mukhopadhyay P,Lakshmanan I,Ponnusamy MP,Chakraborty S,Jain M,Pai P,Smith LM,Lele SM,Batra SK
40-2300 was used in immunohistochemistry to investigate the functional role of MUC4 in breast cancers.
Fri Sep 06 00:00:00 UTC 2013
MUC4 overexpression augments cell migration and metastasis through EGFR family proteins in triple negative breast cancer cells.
PloS one
Mukhopadhyay P,Lakshmanan I,Ponnusamy MP,Chakraborty S,Jain M,Pai P,Smith LM,Lele SM,Batra SK
40-2300 was used in immunohistochemistry to investigate the functional role of MUC4 in breast cancers.
Fri Sep 06 00:00:00 UTC 2013
Liver X receptor activation enhances blood-brain barrier integrity in the ischemic brain and increases the abundance of ATP-binding cassette transporters ABCB1 and ABCC1 on brain capillary cells.
Brain pathology (Zurich, Switzerland)
ElAli A,Hermann DM
40-2300 was used in western blot to investigate the role of liver X receptors in ischemic cerebral vessels.
Thu Mar 01 00:00:00 UTC 2012
Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death.
Investigative ophthalmology & visual science
Cammas L,Wolfe J,Choi SY,Dedhar S,Beggs HE
40-2300 was used in immunohistochemistry (paraffin) to determine the function of integrin-linked kinase in the mouse lens.
Thu May 17 00:00:00 UTC 2012
The LKB1 tumor suppressor controls spindle orientation and localization of activated AMPK in mitotic epithelial cells.
PloS one
Wei C,Bhattaram VK,Igwe JC,Fleming E,Tirnauer JS
40-2300 was used in immunocytochemistry to report that a germline LKB mutation in mice impairs spindle orientation in cells of the upper gastrointestinal tract and causes dramatic mislocalization of AMPK in mitotic cells.
Wed Jan 16 00:00:00 UTC 2013
C-reactive protein increases BBB permeability: implications for obesity and neuroinflammation.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Hsuchou H,Kastin AJ,Mishra PK,Pan W
40-2300 was used in Western Blot to determine how C-reactive protein interacts with the blood-brain barrier and whether it deters leptin from reaching CNS targets.
Mon Sep 08 00:00:00 UTC 2014
Evidence for phenotypic plasticity in aggressive triple-negative breast cancer: human biology is recapitulated by a novel model system.
PloS one
D'Amato NC,Ostrander JH,Bowie ML,Sistrunk C,Borowsky A,Cardiff RD,Bell K,Young LJ,Simin K,Bachelder RE,Delrow J,Dawson A,Yee LD,Mrózek K,Clay TM,Osada T,Seewaldt VL
40-2300 was used in western blot to use a novel cell-based model system to study phenotypic plasticity in triple-negative breast cancer.
Tue May 07 00:00:00 UTC 2013
Lung self-assembly is modulated by tissue surface tensions.
American journal of respiratory cell and molecular biology
Schwarz MA,Zheng H,Legan S,Foty RA
40-2300 was used in immunohistochemistry to use an in vitro model of lung morphogenesis to identify cell-intrinsic properties that facilitate interaction between epithelial endodermal and mesenchymal mesodermal cells
Sun May 01 00:00:00 UTC 2011
S-Adenosylmethionine regulates connexins sub-types expressed by hepatocytes.
European journal of cell biology
Yamaji S,Droggiti A,Lu SC,Martinez-Chantar ML,Warner A,Varela-Rey M
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Western Blot
Fri Apr 01 00:00:00 UTC 2011
S-Adenosylmethionine regulates connexins sub-types expressed by hepatocytes.
European journal of cell biology
Yamaji S,Droggiti A,Lu SC,Martinez-Chantar ML,Warner A,Varela-Rey M
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Western Blot
Fri Apr 01 00:00:00 UTC 2011
S-Adenosylmethionine regulates connexins sub-types expressed by hepatocytes.
European journal of cell biology
Yamaji S,Droggiti A,Lu SC,Martinez-Chantar ML,Warner A,Varela-Rey M
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Western Blot
Fri Apr 01 00:00:00 UTC 2011
S-Adenosylmethionine regulates connexins sub-types expressed by hepatocytes.
European journal of cell biology
Yamaji S,Droggiti A,Lu SC,Martinez-Chantar ML,Warner A,Varela-Rey M
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Western Blot
Fri Apr 01 00:00:00 UTC 2011
S-Adenosylmethionine regulates connexins sub-types expressed by hepatocytes.
European journal of cell biology
Yamaji S,Droggiti A,Lu SC,Martinez-Chantar ML,Warner A,Varela-Rey M
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Western Blot
Fri Apr 01 00:00:00 UTC 2011
Cx50 requires an intact PDZ-binding motif and ZO-1 for the formation of functional intercellular channels.
Molecular biology of the cell
Chai Z,Goodenough DA,Paul DL
40-2300 was used in immunocytochemistry to investigate the interactions between the PDZ domain-binding motifs of connexins and the scaffolding protein ZO-1
Thu Dec 01 00:00:00 UTC 2011
The tight junction scaffolding protein cingulin regulates neural crest cell migration.
Developmental dynamics : an official publication of the American Association of Anatomists
Wu CY,Jhingory S,Taneyhill LA
40-2300 was used in immunohistochemistry to demonstrate that cingulin is critical for neural crest migration.
Sat Oct 01 00:00:00 UTC 2011
Renal ischemia-reperfusion injury causes intercalated cell-specific disruption of occludin in the collecting duct.
Histochemistry and cell biology
Lee SY,Shin JA,Kwon HM,Weiner ID,Han KH
40-2300 was used in immunohistochemistry (paraffin) to determine the effects of ischemia-reperfusion injury on expression and distribution of the tight junction proteins in rat kidney.
Thu Dec 01 00:00:00 UTC 2011
Renal ischemia-reperfusion injury causes intercalated cell-specific disruption of occludin in the collecting duct.
Histochemistry and cell biology
Lee SY,Shin JA,Kwon HM,Weiner ID,Han KH
40-2300 was used in immunohistochemistry (paraffin) to determine the effects of ischemia-reperfusion injury on expression and distribution of the tight junction proteins in rat kidney.
Thu Dec 01 00:00:00 UTC 2011
The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.
Cancer research
Liu M,Sakamaki T,Casimiro MC,Willmarth NE,Quong AA,Ju X,Ojeifo J,Jiao X,Yeow WS,Katiyar S,Shirley LA,Joyce D,Lisanti MP,Albanese C,Pestell RG
Wed Dec 15 00:00:00 UTC 2010
The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.
Cancer research
Liu M,Sakamaki T,Casimiro MC,Willmarth NE,Quong AA,Ju X,Ojeifo J,Jiao X,Yeow WS,Katiyar S,Shirley LA,Joyce D,Lisanti MP,Albanese C,Pestell RG
Wed Dec 15 00:00:00 UTC 2010
Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-beta-dependent mechanisms.
Liver international : official journal of the International Association for the Study of the Liver
Copple BL
40-2300 was used in immunocytochemistry to test if hypoxia stimulates hepatocyte epithelial to mesenchymal transition via a HIF-dependent mechanism
Sat May 01 00:00:00 UTC 2010
Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-beta-dependent mechanisms.
Liver international : official journal of the International Association for the Study of the Liver
Copple BL
40-2300 was used in immunocytochemistry to test if hypoxia stimulates hepatocyte epithelial to mesenchymal transition via a HIF-dependent mechanism
Sat May 01 00:00:00 UTC 2010
Normalization of wound healing and diabetic markers in organ cultured human diabetic corneas by adenoviral delivery of c-Met gene.
Investigative ophthalmology & visual science
Saghizadeh M,Kramerov AA,Yu FS,Castro MG,Ljubimov AV
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Thu Apr 01 00:00:00 UTC 2010
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes.
Brain research bulletin
Saghizadeh M,Kramerov AA,Yaghoobzadeh Y,Hu J,Ljubimova JY,Black KL,Castro MG,Ljubimov AV
Published figure using ZO-1 polyclonal antibody (Product # 40-2300) in Immunofluorescence
Mon Feb 15 00:00:00 UTC 2010
Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature.
BMC developmental biology
Kim H,Nguyen VP,Petrova TV,Cruz M,Alitalo K,Dumont DJ
40-2300 was used in western blot to investigate the function of Prox1 in vascular endothelial cells in vivo
Mon Jun 28 00:00:00 UTC 2010
Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature.
BMC developmental biology
Kim H,Nguyen VP,Petrova TV,Cruz M,Alitalo K,Dumont DJ
40-2300 was used in western blot to investigate the function of Prox1 in vascular endothelial cells in vivo
Mon Jun 28 00:00:00 UTC 2010
Disruptions of occludin and claudin-5 in brain endothelial cells in vitro and in brains of mice with acute liver failure.
Hepatology (Baltimore, Md.)
Chen F,Ohashi N,Li W,Eckman C,Nguyen JH
40-2300 was used in western blot to explore the vasogenic mechanisms of brain edema
Tue Dec 01 00:00:00 UTC 2009
Disruptions of occludin and claudin-5 in brain endothelial cells in vitro and in brains of mice with acute liver failure.
Hepatology (Baltimore, Md.)
Chen F,Ohashi N,Li W,Eckman C,Nguyen JH
40-2300 was used in western blot to explore the vasogenic mechanisms of brain edema
Tue Dec 01 00:00:00 UTC 2009
Depletion of passenger leukocytes from corneal grafts: an effective means of promoting transplant survival?
Investigative ophthalmology & visual science
Zhang X,Shen L,Jin Y,Saban DR,Chauhan SK,Dana R
40-2300 was used in immunohistochemistry to develop and compare strategies for depleting graft-derived passenger leukocytes before corneal transplantation
Wed Jul 01 00:00:00 UTC 2009
Zonula occludens-1, occludin, and E-cadherin protein expression in biliary tract cancers.
Pathology oncology research : POR
Németh Z,Szász AM,Somorácz A,Tátrai P,Németh J,Gyorffy H,Szíjártó A,Kupcsulik P,Kiss A,Schaff Z
40-2300 was used in immunohistochemistry - paraffin section to examine ZO-1, occludin, and E-cadherin expression in normal and neoplastic biliary tract samples
Tue Sep 01 00:00:00 UTC 2009
Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state.
Developmental biology
Marose TD,Merkel CE,McMahon AP,Carroll TJ
40-2300 was used in immunohistochemistry - frozen section to describe a role for beta-catenin in kidney development
Fri Feb 01 00:00:00 UTC 2008
Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state.
Developmental biology
Marose TD,Merkel CE,McMahon AP,Carroll TJ
40-2300 was used in immunohistochemistry - frozen section to describe a role for beta-catenin in kidney development
Fri Feb 01 00:00:00 UTC 2008
ZO-1 is required for protein kinase C gamma-driven disassembly of connexin 43.
Cellular signalling
Akoyev V,Takemoto DJ
40-2300 was used in immunocytochemistry and western blot to determine the specific role of zonula occludens protein-1 in PKC-gamma-driven connexin43 disassembly
Tue May 01 00:00:00 UTC 2007
Expression of zonula occludens-1 (ZO-1) and the transcription factor ZO-1-associated nucleic acid-binding protein (ZONAB)-MsY3 in glial cells and colocalization at oligodendrocyte and astrocyte gap junctions in mouse brain.
The European journal of neuroscience
Penes MC,Li X,Nagy JI
Fri Jul 01 00:00:00 UTC 2005
Expression of zonula occludens-1 (ZO-1) and the transcription factor ZO-1-associated nucleic acid-binding protein (ZONAB)-MsY3 in glial cells and colocalization at oligodendrocyte and astrocyte gap junctions in mouse brain.
The European journal of neuroscience
Penes MC,Li X,Nagy JI
Fri Jul 01 00:00:00 UTC 2005
