Proteintech

acetylated Tubulin(Lys40) Monoclonal Antibody (7E5H8)

acetylated Tubulin(Lys40) Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 18

acetylated Tubulin(Lys40) Antibody (66200-1-IG) in ICC/IF

Immunofluorescent images of MDCK cells stained for IFT88 rabbit pAb (13967-1-AP) and acetylated tubulin mouse mAb (66200-1-IG) at dilution of 1:50, further stained with Alexa Fluor 594-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L) for 13967-1-AP, and Alexa Fluor 488-conjugated AffiniPure Goat anti-Mouse IGG (H+L) for 66200-1-IG.

acetylated Tubulin(Lys40) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

acetylated Tubulin(Lys40) Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

acetylated Tubulin(Lys40) Antibody in Western Blot (WB)

Product Image Gallery

Product Details

66200-1-IG

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:10,000

View 39 publications 39 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 36 publications 36 publications

Not applicable (N/A)

View 3 publications 3 publications

Product Specifications

Species Reactivity

Dog, Human, Mouse, Pig, Rat

Published species

Fruit fly, Human, Mouse

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

7E5H8

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.7 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody is specific to the acetylated tubulin; it does not recognize non-acetylated tubulin.

Target Information

Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

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Optimization of Primary Human Bronchial Epithelial 3D Cell Culture with Donor-Matched Fibroblasts and Comparison of Two Different Culture Media.

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Homozygous frameshift variant in POC1B causes male infertility with oligoasthenoteratozoospermia in human and mice.

Human molecular genetics

Hua J,Xu B,Liu W,Shi J,Jiang H,Zha X,Zhang X,Wan Y

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Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling.

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Tue Jan 17 00:00:00 UTC 2023

Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling.

The Journal of clinical investigation

Lee D,Gimple RC,Wu X,Prager BC,Qiu Z,Wu Q,Daggubati V,Mariappan A,Gopalakrishnan J,Sarkisian MR,Raleigh DR,Rich JN

Tue Jan 17 00:00:00 UTC 2023

Scanning electron microscopy of human islet cilia.

Proceedings of the National Academy of Sciences of the United States of America

Polino AJ,Sviben S,Melena I,Piston DW,Hughes JW

Tue May 30 00:00:00 UTC 2023

Oral exposure to polystyrene nanoplastics reduced male fertility and even caused male infertility by inducing testicular and sperm toxicities in mice.

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Sat Jul 15 00:00:00 UTC 2023

NLRP3 Inflammasome Mediates Silica-induced Lung Epithelial Injury and Aberrant Regeneration in Lung Stem/Progenitor Cell-derived Organotypic Models.

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Zhou H,Zhang Q,Huang W,Zhou S,Wang Y,Zeng X,Wang H,Xie W,Kong H

Tue Apr 18 00:00:00 UTC 2023

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Grande V,Schuld J,van der Ven PFM,Gruss OJ,Fürst DO

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Lin R,Yang Y,Wu E,Zhou M,Wang S,Zhang Q

Sun Jan 01 00:00:00 UTC 2023

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Wed Dec 07 00:00:00 UTC 2022

Islet primary cilia motility controls insulin secretion.

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Cho JH,Li ZA,Zhu L,Muegge BD,Roseman HF,Lee EY,Utterback T,Woodhams LG,Bayly PV,Hughes JW

Fri Sep 23 00:00:00 UTC 2022

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Thu Sep 01 00:00:00 UTC 2022

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Endothelial RGS12 governs angiogenesis in inflammatory arthritis by controlling cilia formation and elongation via MYCBP2 signaling.

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A Charcot-Marie-Tooth-Causing Mutation in HSPB1 Decreases Cell Adaptation to Repeated Stress by Disrupting Autophagic Clearance of Misfolded Proteins.

Cells

Zhang X,Qiao Y,Han R,Gao Y,Yang X,Zhang Y,Wan Y,Yu W,Pan X,Xing J

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Fluorescence imaging of beta cell primary cilia.

Frontiers in endocrinology

Li ZA,Cho JH,Woodhams LG,Hughes JW

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Biallelic mutations in spermatogenesis and centriole-associated 1 like (SPATC1L) cause acephalic spermatozoa syndrome and male infertility.

Asian journal of andrology

Li YZ,Li N,Liu WS,Sha YW,Wu RF,Tang YL,Zhu XS,Wei XL,Zhang XY,Wang YF,Lu ZX,Zhang FX

Mon Jan 24 00:00:00 UTC 2022

The acetylome of adult mouse sciatic nerve.

Journal of neurochemistry

Shen M,Chen Z,Ming M,Cheng Z,Sun J,Liang Q,Shang T,Zhang Q,Zhou S,Ji Y,Ding F

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Frontiers in pharmacology

Hou Q,Kan S,Wang Z,Shi J,Zeng C,Yang D,Jiang S,Liu Z

Tue Aug 02 00:00:00 UTC 2022

Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis.

Journal of oral microbiology

Wang L,Pu W,Wang C,Lei L,Li H

Fri Apr 29 00:00:00 UTC 2022

Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis.

Journal of oral microbiology

Wang L,Pu W,Wang C,Lei L,Li H

Fri Apr 29 00:00:00 UTC 2022

Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis.

Journal of oral microbiology

Wang L,Pu W,Wang C,Lei L,Li H

Fri Apr 29 00:00:00 UTC 2022

Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis.

Journal of oral microbiology

Wang L,Pu W,Wang C,Lei L,Li H

Fri Apr 29 00:00:00 UTC 2022

SIRT2-knockdown rescues GARS-induced Charcot-Marie-Tooth neuropathy.

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Zhao Y,Xie L,Shen C,Qi Q,Qin Y,Xing J,Zhou D,Qi Y,Yan Z,Lin X,Dai R,Lin J,Yu W

Tue Jun 01 00:00:00 UTC 2021

Phosphosite T674A mutation in kinesin family member 3A fails to reproduce tissue and ciliary defects characteristic of CILK1 loss of function.

Developmental dynamics : an official publication of the American Association of Anatomists

Gailey CD,Wang EJ,Jin L,Ahmadi S,Brautigan DL,Li X,Xu W,Scott MM,Fu Z

Mon Feb 01 00:00:00 UTC 2021

Sub-toxic levels of cobalt ions impair chondrocyte mechanostranduction via HDAC6-dependent primary cilia shortening.

Biochemical and biophysical research communications

Wu H,Wang Z,Liu S,Meng H,Liu S,Fu S

Fri Mar 12 00:00:00 UTC 2021

Pathogenic Variants in ACTRT1 Cause Acephalic Spermatozoa Syndrome.

Frontiers in cell and developmental biology

Sha Y,Liu W,Li L,Serafimovski M,Isachenko V,Li Y,Chen J,Zhao B,Wang Y,Wei X

Tue Aug 24 00:00:00 UTC 2021

Analysis of Key Distinct Biological Characteristics of Human Placenta-Derived Mesenchymal Stromal Cells and Individual Heterogeneity Attributing to Donors.

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Tai C,Wang L,Xie Y,Gao T,Huang F,Wang B

Mon Jan 17 00:00:00 UTC 2022

Biallelic mutations of CFAP58 are associated with multiple morphological abnormalities of the sperm flagella.

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Sha Y,Sha Y,Liu W,Zhu X,Weng M,Zhang X,Wang Y,Zhou H

Mon Mar 01 00:00:00 UTC 2021

Nasal ciliated cells are primary targets for SARS-CoV-2 replication in the early stage of COVID-19.

The Journal of clinical investigation

Ahn JH,Kim J,Hong SP,Choi SY,Yang MJ,Ju YS,Kim YT,Kim HM,Rahman MDT,Chung MK,Hong SD,Bae H,Lee CS,Koh GY

Thu Jul 01 00:00:00 UTC 2021

The histone deacetylase inhibitor PCI-24781 impairs calcium influx and inhibits proliferation and metastasis in breast cancer.

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Yang T,Wang P,Yin X,Zhang J,Huo M,Gao J,Li G,Teng X,Yu H,Huang W,Wang Y

Mon Aug 16 00:00:00 UTC 2021

UTX/KDM6A deletion promotes the recovery of spinal cord injury by epigenetically triggering intrinsic neural regeneration.

Molecular therapy. Methods & clinical development

Guo Z,Li C,Cao Y,Qin T,Jiang L,Xu Y,Li M,Luo Z,Hu J,Lu H

Fri Mar 12 00:00:00 UTC 2021

UTX/KDM6A deletion promotes the recovery of spinal cord injury by epigenetically triggering intrinsic neural regeneration.

Molecular therapy. Methods & clinical development

Guo Z,Li C,Cao Y,Qin T,Jiang L,Xu Y,Li M,Luo Z,Hu J,Lu H

Fri Mar 12 00:00:00 UTC 2021

Mutations in DNAH8 contribute to multiple morphological abnormalities of sperm flagella and male infertility.

Acta biochimica et biophysica Sinica

Weng M,Sha Y,Zeng YU,Huang N,Liu W,Zhang X,Zhou H

Fri Mar 26 00:00:00 UTC 2021

Biallelic mutations in KATNAL2 cause male infertility due to oligo-astheno-teratozoospermia.

Clinical genetics

Wei X,Liu W,Zhu X,Li Y,Zhang X,Chen J,Isachenko V,Sha Y,Lu Z

Fri Oct 01 00:00:00 UTC 2021

Biallelic mutations in KATNAL2 cause male infertility due to oligo-astheno-teratozoospermia.

Clinical genetics

Wei X,Liu W,Zhu X,Li Y,Zhang X,Chen J,Isachenko V,Sha Y,Lu Z

Fri Oct 01 00:00:00 UTC 2021

MiR-107 confers chemoresistance to colorectal cancer by targeting calcium-binding protein 39.

British journal of cancer

Liang Y,Zhu D,Hou L,Wang Y,Huang X,Zhou C,Zhu L,Wang Y,Li L,Gu Y,Luo M,Wang J,Meng X

Sun Mar 01 00:00:00 UTC 2020

HDAC11 promotes meiotic apparatus assembly during mouse oocyte maturation via decreasing H4K16 and α-tubulin acetylation.

Cell cycle (Georgetown, Tex.)

Sui L,Zhang S,Huang R,Li Z

Sat Feb 01 00:00:00 UTC 2020

Mutations of MAP1B encoding a microtubule-associated phosphoprotein cause sensorineural hearing loss.

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Cui L,Zheng J,Zhao Q,Chen JR,Liu H,Peng G,Wu Y,Chen C,He Q,Shi H,Yin S,Friedman RA,Chen Y,Guan MX

Thu Dec 03 00:00:00 UTC 2020

Improved early development potence of in vitro fertilization embryos by treatment with tubacin increasing acetylated tubulin of matured porcine oocytes.

Mechanisms of development

Sun J,Cui K,Li ZP,Gao B,Huang B,Liu Q,Shi D

Tue Dec 01 00:00:00 UTC 2020

Loss-of-function mutations in centrosomal protein 112 is associated with human acephalic spermatozoa phenotype.

Clinical genetics

Sha Y,Wang X,Yuan J,Zhu X,Su Z,Zhang X,Xu X,Wei X

Sat Feb 01 00:00:00 UTC 2020

HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.

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Zhan Y,Wang H,Zhang L,Pei F,Chen Z

Fri Dec 18 00:00:00 UTC 2020

HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.

Frontiers in cell and developmental biology

Zhan Y,Wang H,Zhang L,Pei F,Chen Z

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Alternatively Polarized Macrophages Regulate the Growth and Differentiation of Ependymal Stem Cells through the SIRT2 Pathway.

Experimental neurobiology

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Thu Apr 30 00:00:00 UTC 2020

Photo-triggered self-destructive ROS-responsive nanoparticles of high paclitaxel/chlorin e6 co-loading capacity for synergetic chemo-photodynamic therapy.

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Fri Jul 10 00:00:00 UTC 2020

EBV-miR-BART12 accelerates migration and invasion in EBV-associated cancer cells by targeting tubulin polymerization-promoting protein 1.

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Wu Y,Wang D,Wei F,Xiong F,Zhang S,Gong Z,Shi L,Li X,Xiang B,Ma J,Deng H,He Y,Liao Q,Zhang W,Li X,Li Y,Guo C,Zeng Z,Li G,Xiong W

Tue Dec 01 00:00:00 UTC 2020

UNG2 deacetylation confers cancer cell resistance to hydrogen peroxide-induced cytotoxicity.

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Fri Nov 20 00:00:00 UTC 2020

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Cellular and molecular neurobiology

Wu Z,Zhang Y,Zhang Y,Zhao P

Wed Apr 01 00:00:00 UTC 2020

KIAA1199 promotes metastasis of colorectal cancer cells via microtubule destabilization regulated by a PP2A/stathmin pathway.

Oncogene

Zhao L,Zhang D,Shen Q,Jin M,Lin Z,Ma H,Huang S,Zhou P,Wu G,Zhang T

Fri Feb 01 00:00:00 UTC 2019

KIAA1199 promotes metastasis of colorectal cancer cells via microtubule destabilization regulated by a PP2A/stathmin pathway.

Oncogene

Zhao L,Zhang D,Shen Q,Jin M,Lin Z,Ma H,Huang S,Zhou P,Wu G,Zhang T

Fri Feb 01 00:00:00 UTC 2019

Biallelic mutations in PMFBP1 cause acephalic spermatozoa.

Clinical genetics

Sha YW,Wang X,Xu X,Ding L,Liu WS,Li P,Su ZY,Chen J,Mei LB,Zheng LK,Wang HL,Kong SB,You M,Wu JF

Fri Feb 01 00:00:00 UTC 2019

Biallelic mutations in PMFBP1 cause acephalic spermatozoa.

Clinical genetics

Sha YW,Wang X,Xu X,Ding L,Liu WS,Li P,Su ZY,Chen J,Mei LB,Zheng LK,Wang HL,Kong SB,You M,Wu JF

Fri Feb 01 00:00:00 UTC 2019

Biallelic mutations in PMFBP1 cause acephalic spermatozoa.

Clinical genetics

Sha YW,Wang X,Xu X,Ding L,Liu WS,Li P,Su ZY,Chen J,Mei LB,Zheng LK,Wang HL,Kong SB,You M,Wu JF

Fri Feb 01 00:00:00 UTC 2019

The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma.

Bioscience reports

Sun X,Xie Y,Sun X,Yao Y,Li H,Li Z,Yao R,Xu K

Fri Mar 29 00:00:00 UTC 2019

Novel IFT140 variants cause spermatogenic dysfunction in humans.

Molecular genetics & genomic medicine

Wang X,Sha YW,Wang WT,Cui YQ,Chen J,Yan W,Hou XT,Mei LB,Yu CC,Wang J

Sun Sep 01 00:00:00 UTC 2019

CCDC9 is identified as a novel candidate gene of severe asthenozoospermia.

Systems biology in reproductive medicine

Sha Y,Xu Y,Wei X,Liu W,Mei L,Lin S,Ji Z,Wang X,Su Z,Qiu P,Chen J,Wang X

Sun Dec 01 00:00:00 UTC 2019

CCDC9 is identified as a novel candidate gene of severe asthenozoospermia.

Systems biology in reproductive medicine

Sha Y,Xu Y,Wei X,Liu W,Mei L,Lin S,Ji Z,Wang X,Su Z,Qiu P,Chen J,Wang X

Sun Dec 01 00:00:00 UTC 2019

Ttc39c is upregulated during skeletal muscle atrophy and modulates ERK1/2 MAP kinase and hedgehog signaling.

Journal of cellular physiology

Hayes CS,Labuzan SA,Menke JA,Haddock AN,Waddell DS

Sun Dec 01 00:00:00 UTC 2019

Interaction of hnRNP K with MAP 1B-LC1 promotes TGF-β1-mediated epithelial to mesenchymal transition in lung cancer cells.

BMC cancer

Li L,Yan S,Zhang H,Zhang M,Huang G,Chen M

Fri Sep 06 00:00:00 UTC 2019

Biallelic mutations in Sperm flagellum 2 cause human multiple morphological abnormalities of the sperm flagella (MMAF) phenotype.

Clinical genetics

Sha Y,Liu W,Wei X,Zhu X,Luo X,Liang L,Guo T

Fri Nov 01 00:00:00 UTC 2019

Biallelic mutations in Sperm flagellum 2 cause human multiple morphological abnormalities of the sperm flagella (MMAF) phenotype.

Clinical genetics

Sha Y,Liu W,Wei X,Zhu X,Luo X,Liang L,Guo T

Fri Nov 01 00:00:00 UTC 2019

SIRT2 Inhibition Results in Meiotic Arrest, Mitochondrial Dysfunction, and Disturbance of Redox Homeostasis during Bovine Oocyte Maturation.

International journal of molecular sciences

Xu D,Wu L,Jiang X,Yang L,Cheng J,Chen H,Hua R,Geng G,Yang L,Li Q

Mon Mar 18 00:00:00 UTC 2019

Stabilized Peptide HDAC Inhibitors Derived from HDAC1 Substrate H3K56 for the Treatment of Cancer Stem-Like Cells In Vivo.

Cancer research

Wang D,Li W,Zhao R,Chen L,Liu N,Tian Y,Zhao H,Xie M,Lu F,Fang Q,Liang W,Yin F,Li Z

Mon Apr 15 00:00:00 UTC 2019

A virus-induced kidney disease model based on organ-on-a-chip: Pathogenesis exploration of virus-related renal dysfunctions.

Biomaterials

Wang J,Wang C,Xu N,Liu ZF,Pang DW,Zhang ZL

Tue Oct 01 00:00:00 UTC 2019

EIF4G1 is a novel candidate gene associated with severe asthenozoospermia.

Molecular genetics & genomic medicine

Sha Y,Liu W,Huang X,Li Y,Ji Z,Mei L,Lin S,Kong S,Lu J,Kong L,Zhu X,Lu Z,Ding L

Thu Aug 01 00:00:00 UTC 2019

EIF4G1 is a novel candidate gene associated with severe asthenozoospermia.

Molecular genetics & genomic medicine

Sha Y,Liu W,Huang X,Li Y,Ji Z,Mei L,Lin S,Kong S,Lu J,Kong L,Zhu X,Lu Z,Ding L

Thu Aug 01 00:00:00 UTC 2019

Novel Mutations in CFAP44 and CFAP43 Cause Multiple Morphological Abnormalities of the Sperm Flagella (MMAF).

Reproductive sciences (Thousand Oaks, Calif.)

Sha YW,Wang X,Xu X,Su ZY,Cui Y,Mei LB,Huang XJ,Chen J,He XM,Ji ZY,Bao H,Yang X,Li P,Li L

Tue Jan 01 00:00:00 UTC 2019

Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury.

Cell stem cell

Tata A,Kobayashi Y,Chow RD,Tran J,Desai A,Massri AJ,McCord TJ,Gunn MD,Tata PR

Thu May 03 00:00:00 UTC 2018

Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury.

Cell stem cell

Tata A,Kobayashi Y,Chow RD,Tran J,Desai A,Massri AJ,McCord TJ,Gunn MD,Tata PR

Thu May 03 00:00:00 UTC 2018

Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates.

Scientific reports

Phadwal K,Kurian D,Salamat MKF,MacRae VE,Diack AB,Manson JC

Tue Jul 03 00:00:00 UTC 2018

Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates.

Scientific reports

Phadwal K,Kurian D,Salamat MKF,MacRae VE,Diack AB,Manson JC

Tue Jul 03 00:00:00 UTC 2018

Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates.

Scientific reports

Phadwal K,Kurian D,Salamat MKF,MacRae VE,Diack AB,Manson JC

Tue Jul 03 00:00:00 UTC 2018

Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates.

Scientific reports

Phadwal K,Kurian D,Salamat MKF,MacRae VE,Diack AB,Manson JC

Tue Jul 03 00:00:00 UTC 2018

Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.

eLife

Zhang DL,Sun YJ,Ma ML,Wang YJ,Lin H,Li RR,Liang ZL,Gao Y,Yang Z,He DF,Lin A,Mo H,Lu YJ,Li MJ,Kong W,Chung KY,Yi F,Li JY,Qin YY,Li J,Thomsen ARB,Kahsai AW,Chen ZJ,Xu ZG,Liu M,Li D,Yu X,Sun JP

Fri Feb 02 00:00:00 UTC 2018

Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.

eLife

Zhang DL,Sun YJ,Ma ML,Wang YJ,Lin H,Li RR,Liang ZL,Gao Y,Yang Z,He DF,Lin A,Mo H,Lu YJ,Li MJ,Kong W,Chung KY,Yi F,Li JY,Qin YY,Li J,Thomsen ARB,Kahsai AW,Chen ZJ,Xu ZG,Liu M,Li D,Yu X,Sun JP

Fri Feb 02 00:00:00 UTC 2018

C11orf70 Mutations Disrupting the Intraflagellar Transport-Dependent Assembly of Multiple Axonemal Dyneins Cause Primary Ciliary Dyskinesia.

American journal of human genetics

Fassad MR,Shoemark A,le Borgne P,Koll F,Patel M,Dixon M,Hayward J,Richardson C,Frost E,Jenkins L,Cullup T,Chung EMK,Lemullois M,Aubusson-Fleury A,Hogg C,Mitchell DR,Tassin AM,Mitchison HM

Thu May 03 00:00:00 UTC 2018

HDAC6 Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of PLIN2 in Drosophila.

Developmental cell

Yan Y,Wang H,Hu M,Jiang L,Wang Y,Liu P,Liang X,Liu J,Li C,Lindström-Battle A,Lam SM,Shui G,Deng WM,Jiao R

Mon Oct 09 00:00:00 UTC 2017

HDAC6 Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of PLIN2 in Drosophila.

Developmental cell

Yan Y,Wang H,Hu M,Jiang L,Wang Y,Liu P,Liang X,Liu J,Li C,Lindström-Battle A,Lam SM,Shui G,Deng WM,Jiao R

Mon Oct 09 00:00:00 UTC 2017

RPGR, a prenylated retinal ciliopathy protein, is targeted to cilia in a prenylation- and PDE6D-dependent manner.

Biology open

Dutta N,Seo S

Thu Sep 15 00:00:00 UTC 2016

RPGR, a prenylated retinal ciliopathy protein, is targeted to cilia in a prenylation- and PDE6D-dependent manner.

Biology open

Dutta N,Seo S

Thu Sep 15 00:00:00 UTC 2016

ProBDNF inhibits collective migration and chemotaxis of rat Schwann cells.

Tissue & cell

Ding YQ,Li XY,Xia GN,Ren HY,Zhou XF,Su BY,Qi JG

Sat Oct 01 00:00:00 UTC 2016

NDUFV2 regulates neuronal migration in the developing cerebral cortex through modulation of the multipolar-bipolar transition.

Brain research

Chen T,Wu Q,Zhang Y,Zhang D

Mon Nov 02 00:00:00 UTC 2015

NDUFV2 regulates neuronal migration in the developing cerebral cortex through modulation of the multipolar-bipolar transition.

Brain research

Chen T,Wu Q,Zhang Y,Zhang D

Mon Nov 02 00:00:00 UTC 2015

NDUFV2 regulates neuronal migration in the developing cerebral cortex through modulation of the multipolar-bipolar transition.

Brain research

Chen T,Wu Q,Zhang Y,Zhang D

Mon Nov 02 00:00:00 UTC 2015

NDUFV2 regulates neuronal migration in the developing cerebral cortex through modulation of the multipolar-bipolar transition.

Brain research

Chen T,Wu Q,Zhang Y,Zhang D

Mon Nov 02 00:00:00 UTC 2015

The oncoprotein HBXIP promotes migration of breast cancer cells via GCN5-mediated microtubule acetylation.

Biochemical and biophysical research communications

Li L,Liu B,Zhang X,Ye L

Fri Mar 13 00:00:00 UTC 2015

The oncoprotein HBXIP promotes migration of breast cancer cells via GCN5-mediated microtubule acetylation.

Biochemical and biophysical research communications

Li L,Liu B,Zhang X,Ye L

Fri Mar 13 00:00:00 UTC 2015

The oncoprotein HBXIP promotes migration of breast cancer cells via GCN5-mediated microtubule acetylation.

Biochemical and biophysical research communications

Li L,Liu B,Zhang X,Ye L

Fri Mar 13 00:00:00 UTC 2015

The oncoprotein HBXIP promotes migration of breast cancer cells via GCN5-mediated microtubule acetylation.

Biochemical and biophysical research communications

Li L,Liu B,Zhang X,Ye L

Fri Mar 13 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: alpha tubulin; alpha-tubulin; Alpha-tubulin 1; Alpha-tubulin 2; Alpha-tubulin 3; Alpha-tubulin 3C; alpha-tubulin 3C/D; Alpha-tubulin 3E; Alpha-tubulin 4; Alpha-tubulin 6; Alpha-tubulin isotype M-alpha-1; Alpha-tubulin isotype M-alpha-2; Alpha-tubulin isotype M-alpha-4; Alpha-tubulin isotype M-alpha-6; Alpha-tubulin ubiquitous; beta-tubulin T beta15 (aa 1-445); class II beta-tubulin isotype; class IIb beta-tubulin; FLJ30169; H2 ALPHA; hum-a-tub1; hum-a-tub2; T beta-15; Talpha1 alpha-tubulin; Testis-specific alpha-tubulin; TUBA1/3/4; Tubulin alpha; tubulin alpha 3; Tubulin alpha chain-like 3; Tubulin alpha-1 chain; Tubulin alpha-1A chain; Tubulin alpha-1B chain; Tubulin alpha-1C chain; Tubulin alpha-2 chain; Tubulin alpha-3 chain; Tubulin alpha-3C chain; Tubulin alpha-3E chain; Tubulin alpha-4 chain; Tubulin alpha-4A chain; Tubulin alpha-6 chain; Tubulin alpha-ubiquitous chain; Tubulin B-alpha-1; Tubulin beta-2B chain; Tubulin H2-alpha; Tubulin K-alpha-1; tubulin, alpha 1; tubulin, alpha 1 (testis specific); tubulin, alpha 1a; tubulin, alpha 1b; tubulin, alpha 1c; tubulin, alpha 2; tubulin, alpha 3c; tubulin, alpha 3e; tubulin, alpha 4; tubulin, alpha 4a; tubulin, alpha 6; tubulin, alpha, brain-specific; tubulin, alpha, ubiquitous; tubulin, alpha-like 3; tubulin, beta 2; tubulin, beta 2B class IIb; tubulin, beta polypeptide paralog

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Gene Aliases: 2410129E14Rik; ALS22; B-ALPHA-1; bA408E5.3; bA506K6.1; bcm948; brdp; H2-ALPHA; K-ALPHA-1; LIS3; M[a]4; M[a]6; PMGYSA; RGD1309427; RGD1565476; Tuba-1; TUBA1; TUBA1A; TUBA1B; TUBA1C; TUBA2; TUBA3; TUBA3C; TUBA3E; Tuba4; TUBA4A; TUBA6; TUBAL3; Tubb2; Tubb2a; TUBB2B

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Function(s)

GTPase activity structural molecule activity structural constituent of cytoskeleton protein binding GTP binding protein domain specific binding double-stranded RNA binding ubiquitin protein ligase binding molecular_function enzyme binding nucleotide binding protein heterodimerization activity

Process(es)

microtubule-based process protein polymerization neuron migration metabolic process biological_process cytoskeleton organization G2/M transition of mitotic cell cycle cytoskeleton-dependent intracellular transport cell division cellular response to interleukin-4 platelet degranulation microtubule cytoskeleton organization

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acetylated Tubulin(Lys40) Monoclonal Antibody (7E5H8)

acetylated Tubulin(Lys40) Antibody (66200-1-IG) in ICC/IF

Product Details

66200-1-IG

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Not applicable (N/A)

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Type

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Conjugate

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Bioinformatics

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