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Alomone Labs, LTD
alpha 1-Syntrophin (SNTA1) Polyclonal Antibody
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FIGURE: 1 / 3
alpha 1-Syntrophin (SNTA1) Antibody (APZ-021-200UL) in IHC (F)
Expression of Syntrophin alpha 1 in mouse neocortex - Immunohistochemical staining of perfusion-fixed frozen mouse brain sections using Anti- alpha 1-Syntrophin (SNTA1) Antibody (#APZ-021), (1:400), followed by Anti-rabbit-AlexaFluor-488 Antibody (green). Syntrophin alpha 1 staining (green) appears in blood vessels (horizontal arrows) and in the pia mater (vertical arrows). Nuclei are stained with DAPI (blu... View More
Product Details
APZ-021-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)RQPSSPGPQPRNLSE, corresponding to amino acid residues 191-205 of mouse alpha 1-syntrophin, Intracellular, PH1 domain
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Syntrophin alpha-1 (Dystrophin, SNTA1) is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 59 kDa dystrophin-associated protein A1 acidic component 1; acidic alpha 1 syntrophin; Alpha-1-syntrophin; alpha1-syntrophin; dystrophin-associated protein A1, 59kDa, acidic component; Pro-TGF-alpha cytoplasmic domain-interacting protein 1; RP23-192L3.1; syntrophin, acidic 1; syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component); Syntrophin-1; TACIP1
Gene Aliases: AW228934; dJ1187J4.5; LQT12; SNT1; SNTA1; TACIP1
UniProt ID: (Human) Q13424
Entrez Gene ID: (Human) 6640, (Mouse) 20648, (Rat) 362242
regulation of heart rate
muscle contraction
regulation of ventricular cardiac muscle cell membrane repolarization
ventricular cardiac muscle cell action potential
negative regulation of peptidyl-cysteine S-nitrosylation
regulation of sodium ion transmembrane transport
regulation of vasoconstriction by circulating norepinephrine
neuromuscular junction development
biological_process
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