Alomone Labs, LTD

alpha 1B-Adrenergic Receptor (extracellular) Polyclonal Antibody, Atto™ 488

View all (11) alpha-1b Adrenergic Receptor antibodies

Promotion

View available promotion(s)

Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

AAR-018-AG-50UL

Applications
Tested Dilution
Publications

Immunocytochemistry (ICC/IF)

Assay-dependent
-

Flow Cytometry (Flow)

10 µg/5x10^5 cells
-
Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

(C)KNANFTGPNQTSSNS, corresponding to amino acid residues 21-35 of human alpha 1B-adrenoceptor, Extracellular, N-terminus
View immunogen

Conjugate

Atto™ 488 Atto™ 488 Atto™ 488

Excitation/Emission Max

501/523 nm

Form

Lyophilized

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 1% BSA

Contains

0.05% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitution: 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Target Information

The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: ADA1B; Adrenergic alpha 1B- receptor; adrenergic receptor, alpha 1b; adrenergic, alpha-1B-, receptor; alpha 1B-adrenoceptor; alpha 1B-adrenoreceptor; Alpha-1B adrenergic receptor; Alpha-1B adrenoceptor; Alpha-1B adrenoreceptor; alpha-1B-adrenergic receptor

View more View less

Gene Aliases: ADRA1; ADRA1B; ALPHA1BAR

View more View less

UniProt ID: (Human) P35368

View more View less

Entrez Gene ID: (Human) 147, (Rat) 24173

View more View less

Function(s)
alpha1-adrenergic receptor activity protein heterodimerization activity
Process(es)
blood vessel remodeling response to amphetamine vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure positive regulation of heart rate by epinephrine-norepinephrine positive regulation of the force of heart contraction by epinephrine-norepinephrine positive regulation of cytosolic calcium ion concentration adult heart development locomotory behavior visual learning response to hormone cell growth regulation of vasoconstriction negative regulation of Rho protein signal transduction organ growth response to drug glucose homeostasis response to morphine positive regulation of MAPK cascade response to estrogen negative regulation of glycogen catabolic process positive regulation of glycogen catabolic process behavioral response to cocaine response to steroid hormone regulation of cardiac muscle contraction adrenergic receptor signaling pathway norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure G-protein coupled receptor signaling pathway adenylate cyclase-modulating G-protein coupled receptor signaling pathway phospholipase C-activating G-protein coupled receptor signaling pathway cell-cell signaling multicellular organism development cell proliferation intracellular signal transduction positive regulation of vasoconstriction positive regulation of smooth muscle contraction adenylate cyclase-activating adrenergic receptor signaling pathway
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support