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Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region.
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Protein Aliases: ADA1D; adrenergic receptor delta1; adrenergic receptor, alpha 1d; adrenergic, alpha -1D-, receptor; adrenergic, alpha-1A-, receptor; adrenergic, alpha-1D-, receptor; alpha 1D-adrenoceptor; alpha 1D-adrenoreceptor; Alpha-1A adrenergic receptor; Alpha-1D adrenergic receptor; Alpha-1D adrenoceptor; Alpha-1D adrenoreceptor; alpha-1D-adrenergic receptor; Alpha-adrenergic receptor 1a; Alpha1delta-AR; RA42
Gene Aliases: ADRA1; ADRA1A; ADRA1D; ADRA1R; Adrd1; ALPHA1; DAR; dJ779E11.2
UniProt ID: (Human) P25100, (Rat) P23944
Entrez Gene ID: (Human) 146, (Rat) 29413
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