Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 1
alpha-1d Adrenoceptor Antibody (PA5-33329) in IHC (P)
Immunohistochemistry analysis of alpha-1d Adrenoceptor in human colon, smooth muscle. Samples were incubated with alpha-1d Adrenoceptor polyclonal antibody (Product # PA5-33329). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Product Details
PA5-33329
Product Specifications
Species Reactivity
Non-human primate,
Pig,
Dog,
Horse,
Guinea pig,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 18 amino acid peptide from 2nd extracellular domain of human ADRA1D.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550712
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Dog, Panda, Horse, Pig, Guinea pig (100%).
Target Information
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ADA1D; adrenergic receptor alpha 1D; adrenergic, alpha -1D-, receptor; adrenergic, alpha-1A-, receptor; adrenergic, alpha-1D-, receptor; adrenoceptor alpha 1D; Alpha-1A adrenergic receptor; Alpha-1D adrenergic receptor; Alpha-1D adrenoceptor; Alpha-1D adrenoreceptor; alpha-1D-adrenergic receptor; Alpha-adrenergic receptor 1a; Alpha1delta-AR
Gene Aliases: ADRA1; ADRA1A; ADRA1D; ADRA1R; ALPHA1; DAR; dJ779E11.2
UniProt ID: (Pig) Q9TTM9, (Human) P25100
Entrez Gene ID: (Pig) 552898, (Human) 146, (Dog) 552897, (Guinea pig) 100735770
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
DNA metabolic process
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
multicellular organism development
cell proliferation
positive regulation of cell proliferation
positive regulation of vasoconstriction
positive regulation of smooth muscle contraction
adenylate cyclase-activating adrenergic receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support