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Invitrogen
alpha N-Catenin Monoclonal Antibody (T.44.7)
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Product Details
MA5-14963
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Monoclonal
Type
Antibody
Clone
T.44.7
Immunogen
Synthetic peptide corresponding to the carboxy-terminal sequence of human a-N-Catenin
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
<0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10987198
Product Specific Information
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with other -alpha-catenin family members.
Target Information
The catenins (alpha, beta, and gamma) are cytoplasmic proteins found in varying abundance in many developing and adult tissues. Catenins bind directly or indirectly to the conserved cytoplasmic tail domain of the cell adhesion cadherins. The association of catenins to cadherins produces a complex, which is linked to the actin filament network. Catenins/cadherin complexes play an important role in mediating cell adhesion, transduction of cell-cell contact positional signals to the cell interior, and may play a crucial role in cell differentiation. Alpha-Catenin (CAP102, 102 kDa), originally described as an E-cadherin associated protein, has been shown to associate with other members of the cadherin family members, N-cadherin and P-cadherin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Alpha N-catenin; alpha(N)-catenin; Alpha-catenin-related protein; alpha-N-catenin; cadherin associated protein; cadherin-associated protein, related; cancer/testis antigen 114; catenin (cadherin-associated protein), alpha 2; catenin alpha 2; Catenin alpha-2; cerebellar deficient folia; DKFZp686H02198; OTTHUMP00000216460; OTTHUMP00000216462
Gene Aliases: AI481747; CAP-R; CAPR; Catna; Catna2; cdf; chp; CT114; CTNNA2; CTNR
UniProt ID: (Human) P26232, (Mouse) Q61301
Entrez Gene ID: (Human) 1496, (Mouse) 12386, (Rat) 297357
cytoskeleton organization
axonogenesis
single organismal cell-cell adhesion
radial glia guided migration of Purkinje cell
dendrite morphogenesis
brain morphogenesis
positive regulation of muscle cell differentiation
regulation of synapse structural plasticity
prepulse inhibition
cell adhesion
multicellular organism development
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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